Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of many anticancer drugs such as platinum compounds, antitubulins (taxanes and vinca alkaloids), bortezomib and thalidomide [1].
Detoxification of opioid addiction during the pregnancy has been avoided since 1970 after some reports showed untoward outcome including stillbirth and acute narcotic withdrawal syndrome in neonates. It was recommended at that time to avoid detoxification until more data was collected and improved monitoring of fetal homeostasis became available.
During the past 20 years I've been in practice, I have found that all addiction treatments are, in fact, some form of harm reduction. We've yet to find an infallible treatment for addictions and substance use disorders. However, the change in the DSM terminology is very significant.
Background: Methamphetamine abuse and dependence is currently a considerable problem.
Objective: To explain the efficacy of buprenorphine in the quick management of methamphetamine related anxiety and depressive disorders and also methamphetamine withdrawal craving.
Results: 52 mg of buprenorphine is very valuable in the treatment of severe methamphetamine related anxiety and depression and also methamphetamine craving.
Background: Tramadol induced disorder is a new problem.
Objective: To explain the efficacy of low dose of clonidine, baclofen and ibuprofen (NSAID) in the treatment of severe and chronic tramadol dependency (2000 mg daily).
Method: To evaluate the usefulness of non-narcotic drugs in the management of severe tramadol withdrawal symptoms.
The purpose of this paper is to describe the multivariate effects of compensable injury on addictive behaviors, especially in relation to substance abuse. Five case studies are broken down into (a) post-accident addiction and (b) pre-accident addiction. These vignettes indicate that within a personal injury the problem of substance use or abuse is hardly independent of other factors. It is linked to pre-accident factors as well as post-accident adjustment.
Background: Since its U.S. FDA approval in 2002, buprenorphine has been available for maintenance treatment of opiate dependence in primary care physicians' offices. Though buprenorphine was intended to facilitate access to treatment, disparities in utilization have emerged; while buprenorphine treatment is widely used in private care setting, public healthcare integration of buprenorphine lags behind.
Drug addiction remains a challenge in perioperative management for a surgical procedure for anaesthesiologists. Anesthesiologists are increasingly encountering patients with current or previous history of drug abuse in their day-to-day practice, both in the ED (emergency department) or ICU (intensive care unit) and the OR (operating room) [1].
Background: Liver cirrhosis is a major cause of deaths in many developed countries. There is evidence that beverage preference may have modifying influence on liver cirrhosis risk independently of the amount of alcohol consumed.
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