Anemia due to iron deficiency is commonly associated with rickets, but rarely myelofibrosis was seen in infants with rickets in the hypocalcaemic phase. The aim of this review is to elucidate the mechanism of development of myelofibrosis in rickets.
Volume 2 Issue 1 - 2016
60-Year-Old Man with Pheochromocytoma and Clinical Picture of Depression
Introduction: Pheochromocytoma is an adrenal gland tumour, which usually produces catecholamines. The classical triad of clinical symptoms consists of palpitations, headaches and profuse sweating.
Gynecomastia, referred to enlargement of the male's breast tissue is a common finding in boys during childhood.
Kocher-Debre-Semelaigne Syndrome: Response to Thyroxine Replacement Therapy
Introduction: Congenital hypothyroidism with muscular pseudohypertrophy or Kocher-Debre-Semelaigne syndrome is the result of long standing untreated moderate to severe hypothyroidism.
Congenital Generalized Lipodystrophy: A Multisystemic Metabolic Disorder
Introduction: Congenital generalized lipodystrophy or Berardinelli-Seip syndrome is a rare autosomal recessive multisystem disorder characterized by the near absence of subcutaneous and visceral adipose tissue from birth or early infancy with severe insulin resistance.
The Importance of Risk Stratification and Management of Newborn Babies of Women with a History of Graves' disease
Thyroid hormones are important for early brain development. During pregnancy, both maternal and foetal thyroid hormones contribute to foetal brain development. Maternal Graves' can lead to transplacental transfer of antibodies that cause neonatal thyrotoxicosis. Neonatal thyrotoxicosis is rare and a high index of suspicion is needed to diagnose it. Neonatal thyrotoxicosis has significant risk of morbidity and mortality and early recognition is warranted.
Volume 1 Issue 1 - 2015
Protective Effect of Alkaloids from Amaranthus Viridis Linn. Against Hydrogen Peroxide Induced Oxidative Damage in Human Erythrocytes (RBC)
Plants are rich in antioxidants which play an essential role in disease prevention. Amaranthus viridis linn. Is a common medicinal plant, spread throughout the world is used in traditional ayurvedic medicine. The present study was aimed to examine the protective effect of partially purified alkaloids (PPA) from Amaranthus viridis against hydrogen peroxide induced oxidative damage in human erythrocytes in vitro conditons.
Synthesis, storage, secretion, delivery, and utilization of thyroid hormones are dependent upon specific enzymatic activity; inherited disorders may cause thyroid disease.
Purpose: Recently, there have been an increasing number of studies indicating that Florine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a sensitive method in the evaluation of thyroid cancer. This retrospective study aims to assess the value of FDG PET/CT in the evaluation of thyroid cancer and determine the association between serum thyroglobulin (Tg) levels and FDG PET/CT.
Lymph Nodes Close to the Thyroid Isthmus Can Masquerade as Malignant Thyroid Nodules in Chronic Lymphocytic Thyroiditis
We present a 40 year old lady who was previously reviewed in a different center with a neck swelling and a clinical and biochemical picture of post-partum thyroiditis. She underwent a fine-needle aspiration (FNA) biopsy of a hypoechoic isthmus nodule that was reported as being a follicular neoplasm and diagnostic surgery was recommended.
Clinical Aspects of C-Type Natriuretic Peptide on the Cardiovascular System
C-type natriuretic peptide (CNP) is one of the three most important members of the human natriuretic peptide family, sharing with them a highly conserved 17-aminoacid ring structure, essential to elicit its biological actions by binding to its specific receptor NPR-B. CNP acts in a paracrine or autocrine way and it is cleared from plasma circulation by the NPR-C receptor. This is one of the reasons why its plasma levels are usually low.
Active Phytoconstituents for Controlling Hypercholesterolemia: A Review
Hypercholesterolemia is patho-physiological condition of metabolism caused by incessant increase in blood cholesterol levels and might be a possible risk factor for many cardiovascular and its associated diseases. Due to adverse effects and cost inefficiency of medications curing hypercholesterolemic disorders, medicinal plants are providing a cost efficient alternative to reduce the risk factors. Present review is providing data of 22 important medicinal plants species possessing antihypercholesterolemic activity and their active phyto-constituents. It would provide a ready reckoner for the research related to increased cholesterol level in blood. Further efforts should be made to implement these plant based drugs in clinical trials.
An Analytical Study for Early Diagnosis and Treatment of Infants & Children Suffering From Congenital Hypothyroidism in China
Objective: To study the clinical and laboratory characteristics of children suffering from congenital hypothyroidism in China.
Method: 455 cases of congenital hypothyroidism infants were collected from 5 articles were published in 4 china medical journals.
Glutamic Acid Decarboxylase Autoantibodies Role in Reclassifying Diabetes of Adulthood in Basrah
Aim: To determine the prevalence and phenotypic characteristics of diabetes subtypes based on glutamic acid decarboxylase autoantibodies (GADA) status in those newly presented diabetic to the Al-Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah, Southern Iraq.
Diagnosis and management of primary hypothyroidism in Traditional Chinese Medicine (TCM) and Traditional Indian Medicine (Ayurveda)
Primary hypothyroidism is one of the most common endocrine disorders. TCM and Ayurveda are the two giant ancient systems of medicine flourished in China and Indian sub-continent respectively. The term like hypothyroidism is not mentioned in both classical literatures of TCM and Ayurveda but the features nearest to hypothyroidism are described in both.
A 42-year-old woman was referred to us for evaluation of a suspicious mass in her left thyroid gland. She had experienced left anterior neck pain and odynophagia for a few weeks. Ultrasonography (US) demonstrated a heterogenous and hypoechoic mass with bright internal hyperechoic foci and a partial surrounding halo involving the posterior aspect of the left thyroid lobe (Figure 1).
The Association of Previous Hajj Performance on the Diabetes Preparation during the Hajj Season
Methods: A cross-sectional study, collected from the Pilgrimages with diabetes during the Hajj season. Baseline characteristics were collected by a formal interview and the measurements were self-reported. The primary outcome was to evaluate the patients' Hajj readiness and the association of the previous Hajj performance on this outcome.
Results: Of the 262 patients with diabetes participated, 72.9% have type 2, mean age of 53.1 years; mean duration of diabetes is 9.23 years.