Open Access Letter to Editor Article ID: IJCEM-1-110

    Familial Goiter and Related Disorders

    E H Sidibe*, P J Guillausseau, A Warnet, J B Stanbury, J E Dumont

    Synthesis, storage, secretion, delivery, and utilization of thyroid hormones are dependent upon specific enzymatic activity; inherited disorders may cause thyroid disease. Studies of a cretinous patient from consanguine marriage have indicated a limited response to thyrotrophic (TSH), both in synthesis of the specific thyroid protein thyroglobulin and in cell growth and division. Other similar response has been observed in a strain of mice. Familial goiter and hypothyroidism may occur when there is failure of the thyroid cell to transport iodide.


    Published on: Nov 20, 2015 Pages: 48-48

    Full Text PDF Full Text HTML DOI: 10.17352/ijcem.000010
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