2026-05-25T01:22:37Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-1414.000090 2021-07-19 PTZ.JCRO:VOL8

Fresh frozen plasma as a source of plasminogen for ligneous conjunctivitis: Case report and a review of the literature Benjamin J Park David Camoriano Mark C Vital Patricia Chévez-Barrios John D GooseyMarcel Belloso<p>Purpose: To describe management of a patient with ligneous conjunctivitis secondary to plasminogen deficiency and review the literature on treatment with plasminogen.</p><p>Design: Interventional case report.</p><p>Methods: A 6-year-old Caucasian girl developed ligneous conjunctivitis recalcitrant to debridement and treatment with topical cyclosporin A and steroids. The literature was reviewed regarding treatment of ligneous conjunctivitis with plasminogen.</p><p>Results: The patient was treated with plasminogen containing drops derived from her father’s fresh frozen plasma. The ligneous conjunctivitis resolved, and the patient was managed on these drops for the following 8 years, initiating treatment for flares and tapering according to clinical response.</p><p>Conclusions: Plasminogen drops concentrated from fresh frozen plasma are a safe and effective option for long-term treatment of ligneous conjunctivitis.</p> Journal of Clinical Research and Ophthalmology - Peertechz Publications 2021-07-19 Case Report https://doi.org/10.17352/2455-1414.000090 en Copyright © Benjamin J Park et al.