2026-05-14T02:24:56Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-1759.000020 2016-07-04 PTZ.AOR:VOL2

Plexiform Neurofibroma of the Larynx in Children: About an Unusual Case Report R Mahdoufi I Barhmi N Tazi R Sami R Abada M RoubalM Mahtar<p><strong>Introduction: </strong>The plexiform neurofibroma is a rare benign tumor which is often associated to type 1 neurofibromatosis or Von Recklinghausen’s disease. The laryngeal involvement in neurofibromatosis is extremely rare.&nbsp;</p><p>The objective of our report is the consideration of laryngeal neurofibromatosis in the differential diagnosis of dyspnea in infants and children.&nbsp;</p><p><strong>Summary of the clinical case:</strong> We report the case of a 4 year-old child who presented with inspiratory dyspnea. Laryngoscopy revealed a mass obstructing completely the laryngeal vestibule. Pathological examination of the resected tissue revealed a plexiform neurofibroma after immunohistochemical examination. The patient had regular follow up and she remained symptom free.&nbsp;&nbsp;</p><p><strong>Discussion: </strong>There is an association between neurofibromatosis type 1 and plexiform neurofibromas of the larynx. Analysis of the margins of neurofibromas of the larynx associated with neurofibromatosis type 1 may&nbsp; elp predict clinical behavior.</p> Archives of Otolaryngology and Rhinology - Peertechz Publications 2016-07-04 Case Report https://doi.org/10.17352/2455-1759.000020 en Copyright © R Mahdoufi et al.