2026-06-03T06:40:23Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-1759.000052 2017-07-26 PTZ.AOR:VOL3

Evaluation of the efficacy of the utilization of the imipramine for patients with allergic rhinitis Diaa El Din El Hennawi Mohamed Rifaat Ahmed Yasser T Madian Mohammed T El-TabbakhIbrahim Hassan Ibrahim<p><strong>Background:</strong> allergic rhinitis is an infl ammatory process of the upper respiratory tract with a continuous symptom that last for hour or more with symptom affect patient’s work and quality of life.&nbsp;</p><p><strong>Methodology:</strong> a randomized controlled trial in which we enrolled 284 patients with allergic rhinitis for periods longer than 4 days/week and for more than 4 consecutive weeks divided into two groups. Group A (n=142) received Imipramine 75 mg/day for 90 days .Group B (n=142), the control group, received desloratadine 5 mg / day for 90 days.</p><p><strong>Results:</strong> The mean visual analogue score nasal symptoms intensity (sneezing, Nasal obstruction, watery rhinorrhea and itchy nose) showed a statistically signifi cantly improvement in group A (treated with Imipramine) compared with group B (treated with desloratadine) after the same treatment period.</p><p><strong>Conclusion:</strong> Imipramine could be used in treatment patients with allergic rhinitis as it is effective as an antihistaminic besides its main action in reliving psychosocial stresses.</p> Archives of Otolaryngology and Rhinology - Peertechz Publications 2017-07-26 Research Article https://doi.org/10.17352/2455-1759.000052 en Copyright © Diaa El Din El Hennawi et al.