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									<identifier>oai:www.peertechzpublications.org:10.17352/2455-1759.000060</identifier>
									<datestamp>2017-10-14</datestamp>
									<setSpec>PTZ.AOR:VOL3</setSpec>
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									<oai_dc:dc xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:mml="http://www.w3.org/1998/Math/MathML" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
										<dc:title>
										Extent of surgery in chronic rhinosinusitis: primarily focused on nasal polyposis
										</dc:title><dc:creator>Petr Schalek</dc:creator><dc:creator> Lukáš Otruba</dc:creator><dc:creator>Anasuya Guha</dc:creator><dc:description>&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The prevalence of chronic rhinosinusitis with nasal polyps (CRSwNP) is estimated at
around 4% in general population. The population-based studies using rhinoendoscopy have demonstrated
the prevalence of nasal polyposis, with values ranging from 0.5 to 2.7%. If the symptoms and reduction
in the quality of life persists despite adequate conservative therapy, then such patients are indicated for
surgical treatment. This review aims to summarize existing literature and discuss the issue of the extent
of the surgery in polyp disease.&amp;nbsp;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods and Results:&lt;/strong&gt; Forty-fi ve relevant articles were identifi ed using a multi-step search of the
web-based PubMed database from the National Library of Medicine. These included articles published
between January 1985 and December 2016 and separated into three categories according to surgical
intervention: simple polypectomy, complete ESS vs. targeted procedures and extended procedures. The
last category was further subdivided into 5 subgroups and discussed separately; namely: middle turbinate
resection, radical ethmoidectomy (nasalisation), extended endonasal maxillary antrostomy, approaches
through anterior wall of maxillary sinus and Draf 3 frontal sinusotomy.&amp;nbsp;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Due to the considerable lack of randomised controlled trials for the surgical treatment,
the optimal extent of surgery in CRSwNP has not been established yet. Although there are a number of
studies dealing with surgical treatment of CRSwNP, and some data suggests that in cases of severe,
diffuse or recurrent polypoid disease, better outcomes can be achieved by more extensive surgical
approaches, unfortunately a great heterogeneity still exists amongst patients‘ characteristics, design of
studies and disease severity thus making collection of high level of evidence still challenging.&lt;/p&gt;</dc:description>
										<dc:publisher>Archives of Otolaryngology and Rhinology - Peertechz Publications</dc:publisher>
										<dc:date>2017-10-14</dc:date>
										<dc:type>Research Article</dc:type>
										<dc:identifier>https://doi.org/10.17352/2455-1759.000060</dc:identifier>
										<dc:language>en</dc:language>
										<dc:rights>Copyright © Petr Schalek et al.</dc:rights>
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