2026-06-04T20:30:46Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-2283.000008 2015-10-14 PTZ.ACG:VOL1

Mediastinal Tuberculosis Lymphadenitis during Anti-TNF Therapy - Case Report Bruno Cesar da Silva Fabio Carneiro Vosqui Nascimento Sonyara Rauedys Oliveira Lisboa Eduardo Antonio Gonçalves Ramos Valdiana Cristina Surlo Tatiana Senna Galvão Nonato AlvesGenoile Oliveira Santana<p>Tuberculosis is described during the use of monoclonal antibodies against tumour necrosis factor (TNF) for Crohn’s disease treatment. We report a case of a 44 year old man that developed fever, night sweats and weight loss during immunosuppressive and anti-TNF therapy for Crohn’s disease. After extensive investigation we performed mediastinoscopy with biopsy of the paratracheal lymph node. A istopathological study revealed caseous necrosis. The patient improved after therapy against tuberculosis. During anti-TNF therapy, the diagnosis of tuberculosis may be mainly difficult when an atypical location is present. Clinical skills are important mainly in countries where tuberculosis is endemic.</p> Archives of Clinical Gastroenterology - Peertechz Publications 2015-10-14 Case Report https://doi.org/10.17352/2455-2283.000008 en Copyright © Bruno Cesar da Silva et al.