2026-05-14T15:27:50Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-2283.000024 2016-12-08 PTZ.ACG:VOL2

Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia Yoram ElitsurDeborah L Preston<p><strong>Objective:</strong> Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to defi cient obese children from WV. <br></p><p><strong>Design: </strong>Vit D defi cient obese children were prospectively recruited. Exclusion criteria included &lt;8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two&nbsp; <strong>supplement groups: </strong>5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment. <br></p><p><strong>Results: </strong>Sixty obese children were screened of whom 39 (65%) were defi cient (&lt;20ng/ml). Of the 39&nbsp; recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signifi cantly <br></p><p>higher in Group B (p= 0.02), but most reached normal levels (&gt;30ng/ml).&nbsp;</p><p><strong>Conclusions: </strong>Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suffi cient to normalize 25(OH)D levels in Vit D defi cient obese West Virginian children.</p> Archives of Clinical Gastroenterology - Peertechz Publications 2016-12-08 Research Article https://doi.org/10.17352/2455-2283.000024 en Copyright © Yoram Elitsur et al.