2026-06-03T18:30:26Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-2283.000120 2024-02-27 PTZ.ACG:VOL10

Relationship between non-alcoholic fatty liver disease and hepatocarcinoma: An integrative review Andrezza Filgueira CavalcanteLiz Marjorie Batista de Freitas Leite<p>This integrative review explores the connection between Non-Alcoholic Fatty Liver Disease (NAFLD) and Hepatocellular Carcinoma (HCC). NAFLD is characterized by the presence of steatosis in more than 5% of hepatocytes in the absence of excessive alcohol consumption (&gt; 20 g/day in men and &gt; 30 g/day in women) or other chronic liver diseases. On the rise globally, the vast majority is associated with risk factors, mainly obesity and type 2 diabetes mellitus. Advanced NAFLD, including non-alcoholic steatohepatitis, emerges as an important precursor to HCC, in some cases, even before the presence of cirrhosis, due in addition, recent studies highlight NAFLD as a main cause of liver transplantation for HCC. Non-invasive diagnostic methods, such as fibroscan liver elastography, exhibit promise for evaluating hepatic steatosis. Therapeutic interventions aim to slow the progression of NAFLD and mitigate the risks of HCC.</p> Archives of Clinical Gastroenterology - Peertechz Publications 2024-02-27 Literature Review https://doi.org/10.17352/2455-2283.000120 en Copyright © Andrezza Filgueira Cavalcante et al.