2026-05-13T21:54:40Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-3476.000003 2014-09-06 PTZ.GJA:VOL1

Severe Repeated Hypotension Occurred after Rocuronium Administrations in a Morbidly Obese Patient: A Case Report Fabio Silvio Mario Araimo Morselli Paolo Tordiglione Ilaria Scarpa Francesco Zuccarini Giovanni Rosa<p>Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2].</p><p>Its pharmacokinetics and pharmacodynamics can be influenced by different factors as age, inhaled anesthetics, hepatic and renal insufficiency, hypothermia, gender and obesity [3-8].</p><p>Rocuronium has been shown to cause less histamine release and cardiovascular instability than benzylisoquinolinum neuromuscular blocking agents such as atracurium and mivacurium [9], however it can act as an antigen: in our clinical experience three acute reactions occurred after its administration in the same patient.</p> Global Journal of Anesthesiology - Peertechz Publications 2014-09-06 Case Report https://doi.org/10.17352/2455-3476.000003 en Copyright © Fabio Silvio Mario Araimo Morselli et al.