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									<identifier>oai:www.peertechzpublications.org:10.17352/2455-4634.000016</identifier>
									<datestamp>2016-05-13</datestamp>
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										<dc:title>
										Root Canal Disinfection Potential of 5.25% Sodium Hypochlorite, 2% Chlorhexidine and 810nm Diode Laser-A Comparative In vitro Antimicrobial Study
										</dc:title><dc:creator>Amit Arvind Agrawal</dc:creator><dc:creator> Swapnil Kolhe</dc:creator><dc:creator> Amit Sope</dc:creator><dc:creator> Dinesh Erlewad</dc:creator><dc:description>&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The eradication of persisting bacteria, such as Enterococcus faecalis, is crucial for the long-term preservation of the endodontically treated tooth.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Context and Purpose of the study:&lt;/strong&gt; The aim of this research was to evaluate and compare the root canal disinfection potential of 5.25% sodium hypochlorite, 2% chlorhexidine gluconate and 810nm diode laser against control.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results:&lt;/strong&gt; Adjunctive use of chemical disinfection by either 5.25% sodium hypochlorite or 2% chlorhexidine led to 100% microbial eradication as against diode laser which achieved 97.7% reduction as compared to baseline microbial count and 68.42% reduction after mechanical cleaning at the same dilutions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main findings:&lt;/strong&gt; Chemicals used in the study achieved greater disinfection than diode laser irradiation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; 5.25% sodium hypochlorite or 2% chlorhexidine can be efficiently used as an adjuvant to mechanical root canal cleaning.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Brief summary:&lt;/strong&gt; A total of 20 extracted teeth, sectioned at cement-enamel junction, were divided into four groups of five teeth each. Control group: mechanical cleaning only; three test groups: mechanical cleaning followed by disinfection with 5.25% sodium hypochlorite or 2% chlorhexidine or 810nm diode laser. Pre and Post treatment microbial samples were collected and cultured.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Potential Implications:&lt;/strong&gt; A thorough mechanical instrumentation is crucial for success of any endodontic therapy and chemical or laser irradiation will only be helpful as an adjuvant.&lt;/p&gt;</dc:description>
										<dc:publisher>International Journal of Oral and Craniofacial Science - Peertechz Publications</dc:publisher>
										<dc:date>2016-05-13</dc:date>
										<dc:type>Research Article</dc:type>
										<dc:identifier>https://doi.org/10.17352/2455-4634.000016</dc:identifier>
										<dc:language>en</dc:language>
										<dc:rights>Copyright © Amit Arvind Agrawal et al.</dc:rights>
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