2026-04-28T03:26:03Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-5363.000063 2025-03-13 PTZ.GJIDCR:VOL11

The Tudor Sweating Sickness and ME/CFS: A Hypothesis of Pathogenic Evolution and Modern Disease Manifestation Matthew Kovacs<p>This paper presents a novel hypothesis connecting Tudor Sweating Sickness (TSS), which caused five major epidemics in England between 1485 and 1551, with modern Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Through comprehensive analysis of historical records, epidemiological patterns, and clinical presentations, it is proposed that ME/CFS may represent an evolved form of the pathogen responsible for TSS. This analysis reveals striking similarities in demographic distribution, symptom patterns, and physiological mechanisms, suggesting a potential evolutionary link between these conditions.</p> Global Journal of Infectious Diseases and Clinical Research - Peertechz Publications 2025-03-13 Perspective Study https://doi.org/10.17352/2455-5363.000063 en Copyright © Matthew Kovacs et al.