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									<identifier>oai:www.peertechzpublications.org:10.17352/2455-5460.000008</identifier>
									<datestamp>2016-05-05</datestamp>
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										<dc:title>
										From Black Bile to the Bipolar Spectrum: A Historical Review of the Bipolar Affective Disorder Concept
										</dc:title><dc:creator>Justin Thomas</dc:creator><dc:creator>Ian Grey</dc:creator><dc:description>&lt;p&gt;The terms melancholia and mania have their etymologies in classical Greek. Melancholia is derived from&amp;nbsp; ‘melas’ (black) and ‘chole’ (bile), highlighting the term’s origins in pre-Hippocratic humoral&amp;nbsp; theories&amp;nbsp; [ 1 ].&amp;nbsp; Where depression/melancholia&amp;nbsp; was&amp;nbsp; viewed as an excess of black bile, the humoral perspective saw mania as arising from an excess of yellow bile [ 2 ], or a mixture of excessive black and yellow bile [ 3 ]. The exact origins of the term mania however, are not&amp;nbsp; as clear-cut as those outlined for melancholia. The Roman physician, Caelius Aurelianus, proposes several&amp;nbsp; origins&amp;nbsp; for&amp;nbsp; the&amp;nbsp; word&amp;nbsp; mania, including&amp;nbsp; the&amp;nbsp; Greek&amp;nbsp; word ‘ania’, meaning to produce great mental anguish.&amp;nbsp; He also suggests&amp;nbsp; ‘manos’, meaning&amp;nbsp; relaxed or loose, which would approximate to an excessive relaxing of the mind or soul [ 4 ]. There are at&amp;nbsp; least five other etymological candidates proposed by Aurelianus for the word mania and&amp;nbsp; the&amp;nbsp; confusion&amp;nbsp; surrounding&amp;nbsp; the exact etymology is attributed to its varied usage in the pre-Hippocratic poetry and mythologies [ 4 ]. &lt;/p&gt;</dc:description>
										<dc:publisher>Archives of Depression and Anxiety - Peertechz Publications</dc:publisher>
										<dc:date>2016-05-05</dc:date>
										<dc:type>Review Article</dc:type>
										<dc:identifier>https://doi.org/10.17352/2455-5460.000008</dc:identifier>
										<dc:language>en</dc:language>
										<dc:rights>Copyright © Justin Thomas et al.</dc:rights>
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