2026-06-09T20:28:15Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/2455-5495.000029 2017-09-23 PTZ.ARDM:VOL3

Renal-limited lupus-like glomerulonephritis Noemi Esparza Martín Rita Guerra Rodríguez Ernesto Fernández Tagarro Santiago Suria González César García Cantón<p>In&nbsp; the&nbsp; setting&nbsp; of&nbsp; an&nbsp; IgG-dominant&nbsp; immune&nbsp; complex-mediated&nbsp; glomerulonephritis,&nbsp; there&nbsp; are&nbsp; multiple&nbsp; pathological fi ndings that strongly suggest the diagnosis of lupus nephritis (LN) including “full-house” immunofluorescence staining for IgG,&nbsp; IgM,&nbsp; IgA,&nbsp; C3&nbsp; and&nbsp; C1,&nbsp; extraglomerular&nbsp; immune&nbsp; deposits,&nbsp; combined mesangial, subendothelial and subepithelial immune deposits&nbsp;&nbsp; and&nbsp;&nbsp; the&nbsp;&nbsp; presence&nbsp;&nbsp; of&nbsp;&nbsp; endothelial&nbsp;&nbsp; tubuloreticular&nbsp;&nbsp; inclusions (TRI). If at the time of biopsy or during the period of follow-up, the patient displayed no extrarenal manifestations or&nbsp; serological&nbsp; evidence&nbsp; of&nbsp; systemic&nbsp; lupus erythematosus&nbsp; (SLE)&nbsp; it&nbsp; is&nbsp; denominate&nbsp; renal-limited&nbsp; lupus-like&nbsp; glomerulonephritis&nbsp; (RLLN) and there are reports both adults and children. Purpose of&nbsp; the&nbsp; study:&nbsp; Clinical&nbsp; features&nbsp; review&nbsp; of&nbsp; in&nbsp; the&nbsp; peer-reviewed academic literature.</p><p><strong>Results</strong></p><p><strong>Clinical features</strong></p><p>&nbsp; RLLN&nbsp; patients&nbsp; were more&nbsp; often&nbsp; male&nbsp; and&nbsp; they&nbsp; presented&nbsp; with&nbsp; lower-range&nbsp; erythrocyturia,&nbsp; more&nbsp; proteinuria and less complement consumption in the classical&nbsp; pathway&nbsp; than&nbsp; LN&nbsp; patients. </p> Archives of Renal Diseases and Management - Peertechz Publications 2017-09-23 Abstract https://doi.org/10.17352/2455-5495.000029 en Copyright © Noemi Esparza Martín et al.