2026-04-04T11:47:35Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/aaa.000006 2019-10-04 PTZ.AAA:VOL3

Autoimmune hepatitis associated Hepatitis C virus infection treated with fi rst generation direct-acting antivirals Juan Diego Castro Limo Tomas Artaza Varasa Maria Recuero Pradillo Marta Romero-Gutierrez Ana Zaida Gomez Moreno Juan Jose Sanchez Ruano Carlos San Roman Gutierrez Pablo Munoz GomezRafael Gomez Rodríguez<p>The hepatitis C virus (HCV) infection has been associated with autoimmune diseases, probably due to the interaction between HCV E2 envelope protein and CD-81 receptor of B lymphocyte and thus, can infl uence the pathogenesis of autoimmune liver diseases [1,2]. Therefore, it seems reasonable to consider the benefi cial effect of direct-acting antivirals (DAAs) for HCV in patients with chronic HCV infection and autoimmune hepatitis (HAI), although evidence is scarce. We report the case of an HCV-infected patient who developed an HAI triggered by interferon and since then has been treated with DAAs improving liver function and maintaining sustained virologic response (SVR), without immunosuppressive treatment nowadays.</p> Annals of Antivirals and Antiretrovirals - Peertechz Publications 2019-10-04 Case Report https://doi.org/10.17352/aaa.000006 en Copyright © Juan Diego Castro Limo et al.