2026-05-03T02:41:01Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/aadc.000032 2025-12-09 PTZ.AADC:VOL9

Cognitive Development and Grey Matter Enhancement via Auto-Generated Neural Impulse Modulation: A Speculative Framework for Alzheimer’s Risk Reduction Shijo George<p>Grey matter atrophy is a hallmark of Alzheimer’s disease (AD) and related dementias. This paper proposes a theoretical framework describing how “auto-generated neural impulses” (AGNI)—an umbrella term for endogenous stimulation patterns including homeostatic plasticity, neurotrophic regulation, and intrinsic oscillatory reinforcement—might influence grey matter density and cognitive resilience.</p><p>The paper develops non-actionable mathematical models, proposes theoretical molecular pathways, and explores speculative criteria for designing a hypothetical “cognitive-enhancing compound” that could, in theory, support neuroplasticity. These frameworks are intended to inspire academic discussion and are not meant as medical or laboratory protocols.</p> Annals of Alzheimer's and Dementia Care - Peertechz Publications 2025-12-09 Research Article https://doi.org/10.17352/aadc.000032 en Copyright © Shijo George et al.