2026-05-25T21:17:07Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/ahcrr.000017 2019-05-23 PTZ.AHCRR:VOL4

Chronic demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in peripheral T-cell lymphoma Salem Bahashwan Carolyne Croizier Xavier Moisset Romain Guièze Bertrand Evrard Olivier Tournilhac Jacques-Olivier BayRichard Lemal<p>Malignant lymphoma can cause peripheral neuropathy through various mechanisms. We report the case of 67-year-old man with chronic motor and sensory axonal demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in serum and cerebrospinal fluid (CSF) as an initial presentation of peripheral T-cell lymphoma, not otherwise specified. The patient was treated with chemotherapy for T-cell lymphoma, and achieved complete remission.&nbsp; Motor function recovered completely and sensory function improved. Neurological improvement was concurrent with the disappearance of serum and CSF anti-ganglioside GQ1b antibodies. This is the first report of chronic demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in peripheral T-cell lymphoma.</p> Archives of Hematology Case Reports and Reviews - Peertechz Publications 2019-05-23 Case Report https://doi.org/10.17352/ahcrr.000017 en Copyright © Salem Bahashwan et al.