2026-10-07T23:52:54Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/apm.000041 2026-10-02 PTZ.APM:VOL11

Accurate Rickettsia Assays for IgG and IgM Serodiagnosis Lee Fuller<p>It had been recommended in 2020 by the Centers for Disease Control (CDC) that serodiagnosis of acute rickettsiosis specifically utilize the IFA-IgG assay. This was a new and curious requirement for all testing facilities, namely the use of an assay that was neither described in detail nor actually relevant for acute phase diagnosis of a potentially fatal disease. A detailed protocol for this assay should have been included in this announcement to encourage rapid compliance, along with a detailed explanation of the relevance of this specific assay. This was not the case, however, with the result being false-negative IFA-IgG reports over several seasons nationally.</p> Archives of Preventive Medicine - Peertechz Publications 2026-10-02 Commentary https://doi.org/10.17352/apm.000041 en Copyright © Lee Fuller et al.