2026-05-18T05:09:44Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/ijcem.000063 2025-03-28 PTZ.IJCEM:VOL11

Free Triiodothyronine Toxicosis in Adolescent Monozygotic Twin Brothers Mikołaj Kuncewicz Dorota Szydlarska Marta CiechomskaKatarzyna Życińska<p>Free triiodothyronine toxicosis is a rare condition, expressed by isolated triiodothyronine concentration elevation, resulting in an overt hypermetabolic state. Diagnosis and treatment are particularly important&nbsp; in young populations during puberty, with intensive intellectual and physical development. We present a case of monozygotic adolescent male twins, with cardiovascular symptoms, along with anxiety, hypersensitivity and insomnia. The free triiodothyronine toxicosis in the absence of anti-thyroid antibodies. Successful treatment with symptom relief and laboratory results normalization was achieved after 8 weeks of anti-thyroid medication with beta-blocker addition. The described condition may be an early stage of developing disease, so further follow-up is obligatory. Because the case presents an atypical population for the disorder, with brothers additionally being monozygotic twins, genetic factors should be taken into consideration in the event of disease progression.</p> International Journal of Clinical Endocrinology and Metabolism - Peertechz Publications 2025-03-28 Case Report https://doi.org/10.17352/ijcem.000063 en Copyright © Mikołaj Kuncewicz et al.