2026-05-18T05:18:24Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/ijrro.000014 2016-06-22 PTZ.IJRRO:VOL2

Volumetric Modulated Arc Therapy versus Intensity Modulated Radiation Therapy in the Treatment of Prostate Cancer: A Systematic Literature Review Issam Lalya Noha Zaghba Khalid Andaloussi-Saghir Mohamed Elmarjany Laila Baddouh Keltoum Dahmani Khalid Hadadi Hassan SifatHamid Mansouri<p><strong>Aim: </strong>Provide evidence concerning advantages of volumetric modulated arc therapy over intensity modulated radiation therapy. <strong><br></strong></p><p><strong>Background:</strong> External beam radiation therapy is a major treatment modality of prostate cancer; especially in high and intermediate risk categories in combination with androgen deprivation therapy.The&nbsp; advent&nbsp; of&nbsp; new&nbsp; techniques of irradiation such as intensity modulated radiation therapy (IMRT) improved significantly the biochemical free survival by allowing dose escalation without enhancement of&nbsp; related&nbsp; toxicities.Volumetric modulated&nbsp; arc&nbsp; therapy&nbsp; (VMAT)&nbsp; is&nbsp; a&nbsp; circular&nbsp; technique&nbsp; delivering radiation dose using one or multiple arc of 360° around the target volumes.</p><p><strong>Methods: </strong>We&nbsp; collected&nbsp; all&nbsp; dosimetric&nbsp; studies&nbsp; comparing&nbsp; VAMT&nbsp; versus&nbsp; IMRT,&nbsp; published&nbsp; in PubMed&nbsp; indexed&nbsp; journals&nbsp; between&nbsp; 2008&nbsp; and&nbsp; 2015.&nbsp; Parameters&nbsp; of&nbsp; comparison&nbsp; were&nbsp; dose&nbsp; volume histograms for target volumes and organs at risk, number of monitors units and treatment time.</p><p><strong>Results:</strong> Globally, the target volumes coverage and organ at risk protection were similar between the two techniques. VMAT has the advantage to reduce significantly the number of monitor units and treatment time. </p><p><strong>Conclusion:</strong> VMAT is a very efficient technique of radiation therapy, and should be preferred in the treatment of prostate cancer.</p> International Journal of Radiology and Radiation Oncology - Peertechz Publications 2016-06-22 Review Article https://doi.org/10.17352/ijrro.000014 en Copyright © Issam Lalya et al.