2026-04-05T17:58:32Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/jfsnt.000009 2017-09-12 PTZ.JFSNT:VOL3

Serum levels of Vitamin A and Atopic Rhinoconjunctivitis in Swedish adolescents Malin Barman Nils-Gunnar Carlsson Anna Sandin Agnes E. WoldAnn-Sofi e Sandberg<p><strong>Aim</strong>: Vitamin A plays a role in mucosal immunity and tolerance, but the association between vitamin A status and allergy is still unclear. The aim of the study was to analyze the levels of vitamin A in serum from adolescents with or without atopic rhinoconjunctivitis.</p><p><strong>Method</strong>: Thirteen-year-old children with atopic rhinoconjunctivitis (n = 53) and non-allergic, nonsensitized controls (n = 52) were randomly selected from a population based prospective birth cohort comprising 1228 children in Northern Sweden born in 1996-1997. Vitamin A (retinol) concentrations in serum were measured with high performance liquid chromatography mass spectrometry. Multiple logistic regression was used to evaluate the association between allergy prevalence and serum vitamin A levels.</p><p><strong>Results</strong>: Multiple logistic regression analysis showed no association between serum vitamin A levels and atopic rhinoconjunctivitis prevalence; OR = 1.00 (95% confidence interval 1.00-1.00), p = 0.81.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Stratification for gender revealed a trend for a higher risk for having atopic rhinoconjunctivitis with higher concentrations of vitamin A in serum for females, OR = 1.02 (1.00-1.05), p = 0.07. No such associations were found in male subjects OR = 0.99 (0.97-1.01), p = 0.15. A dose-response relationship between allergy and vitamin A concentrations were also calculated but no such relationships were found, neither for all subjects nor for male and females separately.</p><p><strong>Conclusions</strong>: Serum levels of vitamin A could neither be positively nor negatively associated with atopic rhinoconjunctivitis in Swedish teenagers.</p> Journal of Food Science and Nutrition Therapy - Peertechz Publications 2017-09-12 Research Article https://doi.org/10.17352/jfsnt.000009 en Copyright © Malin Barman et al.