2026-05-09T22:30:27Z
https://www.peertechzpublications.org/oai-pmh
oai:www.peertechzpublications.org:10.17352/jgro.000004
2015-12-24
PTZ.JGRO:VOL1
Adult Granulosa Cell Tumours of the Ovary Seven Case Reports
Faten LIMAIEM Saloua MEJRI Imen KHELIL Ahlem LAHMAR Saadia BOURAOUI Sabeh MZABI-REGAYA<p><strong>Background:</strong>Ovarian granulosa cell tumours are low-grade malignant sex cord-stromal tumours. They represent 2 to 3% of all ovarian cancers and occur mainly within the adult population. </p><p><strong>Aim:</strong> to provide an updated overview on ovarian adult granulosa cell tumours.Patients <br></p><p> <strong>Methods:</strong>in our retrospective study, we reviewed seven cases of adult granulosa cell tumours that were diagnosed at the pathology department of Mongi Slim hospital over a fourteen-year period (2002- 2015). Clinical and pathRIiological characteristics were retrospectively analyzed.</p><p><strong>Results:</strong> The patients of our series ranged in age between 39 and 64 years (mean = 53 years). The most common presenting symptom was abnormal uterine bleeding (n=5) followed by pelvic pain (n=4). All patients underwent surgical treatment including total hysterectomy with bilateral salpingo-oophorectomy (n=4), hysterectomy with right salpingo-oophorectomy (n=1) and salpingo-oophorectomy (n=2). Histopathological examination of the surgical specimen confirmed the diagnosis of adult granulosa cell tumour in all cases. <strong><br></strong></p><p><strong>Conclusions:</strong>Adult granulosa cell tumours of the ovary are considered as low grade malignancies with a relatively more favourable prognosis compared with much more commonly encountered epithelial ovarian tumours. A prolonged post-therapeutic follow-up is necessary because of the risk of recurrences.</p>
Journal of Gynecological Research and Obstetrics - Peertechz Publications
2015-12-24
Review Article
https://doi.org/10.17352/jgro.000004
en
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