2026-05-24T21:28:49Z https://www.peertechzpublications.org/oai-pmh

oai:www.peertechzpublications.org:10.17352/sjggt.000014 2018-07-11 PTZ.SJGGT:VOL4

Lenalidomide as potential treatment in small cell neuroendocrine lung cancer with del 5q Paul Hartel<p>Lung cancer is a leading cause of cancer deaths world-wide, with the carcinogens in tobacco smoke playing a major etiologic role. Genetic changes responsible for carcinogenesis include activation of proto-oncogenes and inactivation of tumor suppressor genes. Tumor suppressor gene inactivation is contributed to, in part, by loss of chromosomal DNA. While cytogenetic findings in small cell neuroendocrine lung carcinoma are complex, 5q deletion is among the most frequently identified [1,2].</p> Scientific Journal of Genetics and Gene Therapy - Peertechz Publications 2018-07-11 Mini Review https://doi.org/10.17352/sjggt.000014 en Copyright © Paul Hartel et al.