https://www.healthdisgroup.us/journals/archive-of-gerontology-and-geriatrics-research A Peertechz Open Access Journal en-us 31 Jul, 2025 https://www.healthdisgroup.us/articles/AGGR-10-140.php Cognitive aging research has long been shaped by the Seattle Longitudinal Study (SLS), a six-decade investigation into age-related cognitive changes. This narrative review synthesizes SLS findings, emphasizing its five core objectives: elucidating patterns of cognitive decline, identifying onset ages, characterizing individual differences, determining determinants of variability, and evaluating cognitive interventions. Key SLS insights reveal that fluid intelligence (e.g., perceptual speed, reasoning) declines after age 60, while crystallized intelligence (e.g., verbal comprehension) often remains stable or improves. Individual differences are influenced by education, occupation, lifestyle, and health, with cohort effects indicating that newer generations exhibit improved performance, likely linked to societal advancements. Recent studies challenge the generalizability of SLS, highlighting methodological limitations—such as cultural and demographic homogeneity—and questioning the transferability of cognitive training benefits. Contemporary research advances, including neuroimaging and biomarker identification, offer new perspectives on plasticity and resilience, but face challenges related to reproducibility. The review highlights the importance of cross-cultural studies, the integration of multimodal data, and the development of scalable interventions. By critically assessing SLS’s legacy and addressing gaps in current literature, this work provides a roadmap for advancing cognitive aging science while acknowledging the complexities of applying historical findings to diverse populations. 01 Apr, 2025 https://www.healthdisgroup.us/articles/AGGR-10-139.php With the population aging, it is necessary to train future healthcare professionals to properly care for the growing number of older adults. One challenge is that age stereotypes are commonly found among healthcare professionals, making it difficult to adequately care for this population. Even so, age stereotypes among occupational therapy undergraduate students are rarely explored. Therefore, the objective of this study is to analyze the prevalence of negative age stereotypes in a sample of occupational therapy undergraduate students in Spain. Method: 93 Spanish undergraduate students in occupational therapy completed the Negative Age Stereotypes Assessment Questionnaire (abbreviation from its Spanish name: CENVE), which consists of 15 items and 3 dimensions scale (Health, Temperament and personality and Motivation/social), to evaluate existing age stereotypes. Descriptive analyses of these stereotypes were conducted. Results: The results reveal a high percentage of students reporting negative age stereotypes (between 12.9% and 20.4% of the sample), with negative health stereotypes were the most common dimension (33.4%), and followed by temperament and personality (30.1%) and motivation/social (19.4%). Conclusion: The results suggest a high presence of ageist stereotypes in future occupational therapists, leading to a number of practical implications of the study. 13 Aug, 2024 https://www.healthdisgroup.us/articles/AGGR-9-138.php Previously pathological ageing is known to be mainly associated with the development of cardiovascular disease, which is caused by a combination of socioeconomic, metabolic, behavioural, and environmental risk factors. These include sex differences, age, high blood pressure, obesity, low physical activity, smoking, heavy alcohol consumption, high cholesterol and glucose levels, and diabetes mellitus. All processes occurring in the human body are reflected in biochemical and immunological analyses, which may be markers of early cardiovascular aging. The authors investigated correlations between social factors such as education, work, gender, family life, disability, physical activity, smoking and alcohol, and clinical findings such as coronary heart disease (CHD), postinfarct cardiosclerosis (PICS), chronic heart failure (CHF), diabetes mellitus (DM), body mass index (BMI), glucose levels, total cholesterol (TC) and blood pressure (BP) in older individuals. The authors implemented the basic model using R programming language, RStudio version 2023.09.0+463 on a device running MacBook Air M1, 8 GB RAM to identify the association between clinical data and social life. Also, two mathematical models (1)-(3) were proposed to calculate the correlation in combination with traditional machine learning classifiers between clinical data (biomarkers) and the social life of a patient in the age group of 60-74 years, 75-89 years and 90 and above. 31 May, 2024 https://www.healthdisgroup.us/articles/AGGR-9-137.php Introduction: The World Assembly on Ageing in 2002 came out with ‘The Madrid International Plan of Action on Ageing’ as guidance to member countries of the UN to plan their development policies by focusing on their respective population ageing pattern, current and projected. However, even after over twenty years since the document was signed by UN member countries to address multiple dimensions related to ageing issues, still certain challenges need attention, especially in countries where development resources are a constraint and populations ageing rapidly as seen for instance in South Asia as well as in Southern Africa and South America. Methods: This article based on the available literature, reports, and author’s research reviews the progress of MIPAA globally, specifically in South Asia, and generally in regions of Southern Africa and South America given their certain special similar socioeconomic and demographic characteristics. Result: The challenges faced globally and especially in these regions are analyzed through a review of the implementation of MIPAA. To what extent these specific regions given their circumstances have been able to adopt the long-term strategy of MIPAA and develop a perspective on building a society for all ages by forging partnerships between different stakeholders from a right-based approach is reflected in this discourse. Conclusion: In the context of South Asia specifically and to some extent for other regions, certain suggestions are voiced out in removing respective shortfalls and taking forward the global guidance of MIPAA in the coming years. 10 May, 2024 https://www.healthdisgroup.us/articles/AGGR-9-136.php Introduction: Frailty, characterized by declines in physical, psychological, and social functions, presents challenges to aging populations. While multicomponent exercise programs have shown efficacy, accessibility can be limited. Virtual Reality (VR) technologies, including Metaverse integration, show promise for frailty management. Studies have demonstrated positive impacts from VR on physical function in older adults, but research on Metaverse technologies specifically for frailty remains limited. Aim: This systematic review aimed to explore the utilization of Metaverse technology in frailty management among older individuals. Methods: The systematic review adhered to PRISMA guidelines, searching databases for studies from January 2013 to December 2023. Inclusion criteria focused on Metaverse use for frailty in individuals ≥ 65 years old. Two researchers screened articles, leading to the evaluation of full-text papers. Results: Despite screening 35 articles, none were suitable for data extraction, indicating a gap in the literature regarding the application of Metaverse technologies to frailty management. Conclusion: While Metaverse technologies hold promise for personalized frailty interventions, research in this area is limited. Future studies should focus on evaluating the effectiveness of Metaverse interventions and promoting collaboration between healthcare providers and technology developers to advance frailty management in older individuals. 17 Oct, 2023 https://www.healthdisgroup.us/articles/AGGR-8-135.php Background: Diabetic atherosclerosis (AS) is the main cause of disability and death in diabetes. In the progression of AS, autophagic activity plays an important role. Krüppel-like factor 4 (KLF4) is a member of the zinc finger protein transcription factor family and is believed to play a protective role in the pathogenesis of atherosclerosis. This study aimed to explore the role of KLF4 in diabetic atherosclerosis and the autophagic mechanism. Methods: A diabetic mouse model was established and the expression level of KLF4 protein in the aorta of the mice was detected after a high-fat diet. The effects of KLF4 on cholesterol content, apoptosis, autophagy-related proteins, and the AKT/mTOR signaling pathway of THP-1 macrophages were also evaluated. Results: The expression level of KLF4 protein in the aorta of diabetic mice was decreased. Meanwhile, overexpression of KLF4 in THP-1 macrophages significantly decreased cholesterol accumulation, increased beclin-1 expression, decreased P62 expression, enhanced LC3 fluorescence intensity decreased cell apoptosis and p-mTOR and p-AKT expression were decreased under the condition of high glucose. After the reduction of KLF4 expression, the result is reversed. Conclusion: KLF4 induces autophagy by inhibiting the AKT/mTOR pathway and alleviates cholesterol deposition in THP-1 macrophages under high glucose concentration. 07 Oct, 2023 https://www.healthdisgroup.us/articles/AGGR-8-134.php Objective: This study aims to understand the social representations of elderly people about living with HIV/AIDS. Methods: This is a cross-sectional study, descriptive-analytical, with a qualitative approach and theoretical and methodological support from the Collective Memory Theory and the Social Representations Theory. Conducted with 38 elderly people. It used a questionnaire with sociodemographic data, health conditions, and a script for a semi-structured interview. The data analysis with the support of the QRS NVivo® Software and in the light of Bardin’s Content Analysis. Results: The social representations of elderly persons, about living with HIV were: ruptures, living with treatment and coping with prejudice and the struggle for (over)living: the fear of dying and the spread of the diagnosis. Conclusion: Social representations of the elderly about living with HIV/AIDS are about living with drug treatment, with the disruptions in their lives, health care, self-care, and pain of social arising from prejudice. 20 Jun, 2023 https://www.healthdisgroup.us/articles/AGGR-8-133.php The relationship between basal metabolic rate and weight changes which are a normal part of the human aging process can be represented in holographic form. The purpose of the study is to verify the validity of said representation through the development of the objectives, which are to examine the relationship between the total amount of energy lost and the amount of energy lost per unit of body mass, as well as the relationship that exists between the total amount of energy lost and body mass. There are previous studies that relate the size of living beings with their metabolic rate. Our study provides the foundation for the holographic description of that relationship. The analysis of the data allowed us to generate a coherent description of our notion using the tools at our disposal. According to the results of the study, there is a correlation that can be considered statistically significant between the basal metabolic rate per dry kilogram of an organism and the total amount of energy it expends. Based on this observation, we can conclude that the biological system in question satisfies the conditions of the holographic principle. 15 Mar, 2023 https://www.healthdisgroup.us/articles/AGGR-8-132.php People with intellectual disabilities have seen their life expectancy increase in recent years to match that of the general population. The aging of each person will depend on the events experienced throughout their lives, their illnesses, and the psychosocial aspects of their environment. In spite of this, in the case of people with intellectual disabilities, there is evidence of a peculiar way of aging, with significant changes with respect to the general population that affect the age of onset of the first symptoms of aging, and physical, emotional, and health status changes. This article performs a systematic review of the literature to demonstrate the peculiarities of aging in people with intellectual disabilities, concluding on the need to know these changes to adequately guide professional care and thus improve their quality of life. 03 Mar, 2023 https://www.healthdisgroup.us/articles/AGGR-8-131.php Introduction: Prostatectomy oncological surgery is necessary for the continuity of life, but it has physical consequences (momentary inability to drive, erectile dysfunction), emotional (anxiety about the diagnosis and the consequences of treatment, depression) and psychosocial (feeling of impotence, failure, loss of status in society), which may or may not be transitory. Objective: to identify, through an integrative literature review, the biopsychosocial impacts of Radical Prostatectomy. Methodology: This is an integrative literature review, which included articles related to the proposed theme, published between the years 2012 to 2022, available in full, without language restriction; in addition to theses, dissertations and monographs. For this, the PRISMA guidelines were used, as well as the PICO strategy for the best delineation of the research question and research theme. Results and discussions: In view of the discussion, the study can respond to the objections raised by this research, and can show that the culture of masculinity, with regard to virility, strength, and better performance, composes risk factors for possible impacts on Quality of Life of men undergoing radical prostatectomy. These factors are intrinsically associated with the majority of relationships and characteristics represented by a man. Final considerations: Psychoeducation and general guidelines on sexual and mental health should be carried out to patients who undergo radical therapies, such as radical prostatectomy, so that these patients can achieve coping strategies that make them feel better, contributing directly to the best quality of life, functional capacity, and their social relationships. 13 Oct, 2022 https://www.healthdisgroup.us/articles/AGGR-7-130.php Introduction: Constipation is a common cause of morbidity in the elderly. Its management is particularly challenging in the inpatient population where many factors exacerbate constipation. We describe a Quality Improvement Project to reduce constipation in a Care of the Elderly ward, including conservative measures to complement medical treatment. Aims: To increase bowel motion frequency to at least once every two days in elderly inpatients, and to increase bowel chart documentation. Methods: Weekly monitoring of ward inpatients. Measurements taken were: days since last bowel motion, laxatives prescribed, documentation on bowel charts and ward rounds, and episodes of diarrhea. A new intervention was introduced every two weeks, over a total of 10 weeks. Interventions: The 4 interventions introduced were: 1) Recording bowel motions at the daily ‘Board Round’ Multi-Disciplinary Meeting. 2) Ward staff education sessions. 3) Footstools for use with commodes and toilets. 4) High-fibre foods for patients with constipation. Results: Bowel motion frequency improved, with 100% of patients moving bowels every 2 days from a baseline of 66.6%. Ward round and bowel chart documentation improved to 100% and 92.9% (from 41.6% and 33.3%). Laxative prescriptions increased from 50% to 78.6%, with no increase in episodes of diarrhea. Conclusions: Constipation improved with our interventions but was accompanied by increased laxative prescriptions, which carry a risk of side effects. Our next steps will be to optimize our conservative measures to reduce laxative prescriptions, and to this end, we have developed high-fiber snack boxes to aid constipation in elderly patients. 19 May, 2021 https://www.healthdisgroup.us/articles/AGGR-6-129.php Objective: To comprehensively analyze cases of psychiatric consultation in a general hospital and provide a primary reference for the development of consultation-liaison psychiatry. Method: A retrospective study was conducted by analyzing data collected over a two-year period regarding psychiatric consultations from the inpatient registry in a general hospital. Results: A total of 926 and 774 psychiatric consultations were recorded in 2016 and 2017, respectively. The most common reason for consultation was unexplained somatic symptoms. Consultations based on psychological evaluation, and mental/behavioral disorders due to organic diseases and perioperative stress were significantly higher in 2017 than those in 2016 (P&lt;0.01). Diagnoses of neurotic, stress-related and somatoform disorders were significantly lower in 2017 compared to those in 2016 (269 [34.8%] cases in 2017 vs. 373 [40.3%] cases in 2016; P=0.019). Among specific diagnoses, generalized anxiety disorder was the most common. Conclusion: Most patients with depressive or anxiety disorders visit a general hospital due to somatic symptoms. It is necessary to train non-psychiatrists to identify mental disorders efficiently, as well as to extend the comprehensive consultation model to include more clinical departments. 15 Mar, 2021 https://www.healthdisgroup.us/articles/AGGR-6-128.php Purpose: To evaluate the Quality of Life (QoL), overall satisfaction, neurodegenerative dimension, and the role of comorbidities among men diagnosed with Parkinson’s disease PD, Erectile Dysfunction (ED) and Benign Prostate Hyperplasia (BPH) in the United States. Design: This was an online-based, cross‐sectional survey study. Methods: A cross-sectional survey was conducted to obtain men’s QoL perception of PD, ED, and BPH. A sample of males (N = 46), 40 years of age or older, completed validated questionnaires divided into three domains: International Index of Erectile Function (IIEF-5), International Prostate Symptom Score (IPSS-8), and Parkinson’s Disease Questionnaire (PDQ-39). Chi-Square, and descriptive statistics were used to analyze the data. Findings: Forty-six men were included. Of the responding men, 17 were Caucasian (37 %) and 16 were black (34%). The mean age of the men was 50.7 years, ranging from 40 to 80 years old. In this group of men, the degree of QoL was mild in 8.7 %, moderate in 27 %, and severe in 50%. Based on the responses to the questions, the severity of the symptoms is considered severe. The BPH symptoms score was 34.3 ± 8.2 (p < .05), the PD symptoms score was 157.1 ± 35.6 (p < .05), and the ED symptoms score was 13.4 ± 5.8 (p < .05). Conclusion: Comorbidities advances evidence of deterioration of disease with age, meaning that at substantially older ages, comorbid men faced severe QoL associated with bradykinesia, rigidity, tremors, nocturia, and ED. Future work is needed to further assess this association. Clinical Relevance: This study’s findings could be used as evidence to encourage caregivers to initiate fall and QoL precautions for men diagnosed with PD who presents with ED and BPH. 01 Feb, 2021 https://www.healthdisgroup.us/articles/AGGR-6-127.php Objective: To review the efficacy of the reablement approach in management of older persons. Type of study: This is a review study analyzing the evolvement, effectiveness and the spread out of this model of care for old people. Methods: Relevant previous studies on reablement were identified and critically appraised, providing clarity and enhanced understanding of the topic. Customarily, in the management of the elderly over the years, health and social care have always focused on critical and recurrent conditions while little emphasis is placed on strategies for early detection or prevention of old age-related health challenges. With the world facing the challenge of an aging population with an associated prevalence increase in age-related disabilities, the conception of ‘reablement’ that promotes independence in older adults by optimizing their intrinsic functional abilities is becoming more popular. An integral part of reablement is the interdisciplinary work that is embedded in it. The Reablement model is an all-inclusive approach as it features preventive, rehabilitative, and health promotion. 11 Dec, 2020 https://www.healthdisgroup.us/articles/AGGR-5-126.php Background: COVID-19 outbreaks in long-term care facilities are a significant impact on infection rates and mortality rates of the residents. The study aimed to describe the effectiveness of a COVID-19 prevention and control (CPC) program in a long-term care facility. Methods: A CPC program, including social isolation, active symptoms screening for all residents and staff, SARS-CoV-2 testing for symptomatic individuals, droplet and contact isolation measures for asymptomatic residents, confinement of the unit and clinical care in a separate unit for patients, was implemented in a long-term care facility with two geriatrics and two psychiatric units, with aa total of 300 beds. The attack rate was calculated as the number of COVID-19 confirmed cases divided by the total number of exposed individuals and case fatality rate as the deceased COVID-19 cases divided by the total number of COVID-19 cases. Results: Two geriatric (unit-1 and 2) and one psychiatric (unit-4) units were affected by the outbreak. Attack rates were 26/47(55.3%) for unit-1, 15/29(51.7%) for unit-1and 11/46(23.9%) for unit-4. Case fatality rates were 3/25(12.0%) for unit-1 and 2/16 (12.5%) for unit-2 and no patient from the unit-4 died. Among healthcare professionals, total attack rate was 30/124(24.2%) with no differences between units. Viral pneumonia was present in 13(25%) residents and all healthcare professionals had mild COVID-19. Conclusions: Timely institution of a CPC program with close monitoring of all exposed individuals are essential to decrease the negative outcomes of COVID-19 outbreaks in long-term care facilities. Droplet and contact isolation for all residents is a useful alternative to wide-facility SARS-CoV-2 testing. 05 Aug, 2020 https://www.healthdisgroup.us/articles/AGGR-5-125.php This case report reviews a patient who suffered mixed dementia with depression. The addition of citalopram to the medication regimen was shortly followed by the manifestation of camptocormia, or “bent-spine.” Clinical findings available, without attempting invasive diagnostic procedures, point to a citalopram induced camptocormia. The frequent use of SSRI medications in the geriatric population call for an increased awareness of the possibility of SSRI induced postural side effects. 05 Aug, 2020 https://www.healthdisgroup.us/articles/AGGR-5-124.php High incidence of thrombotic complications was observed in patients with Acute Respiratory Distress Syndrome (ARDS) related to Coronavirus Disease 2019 (COVID-19) [1]. The pathophysiology seems related to systemic thrombophilia by hyper-immune reaction, inducing a “cytokine storm” [1]. 17 Jul, 2020 https://www.healthdisgroup.us/articles/AGGR-5-123.php Starting from the general concept of Agnosia, the present work focuses on the clinical, neurobiological, and functional aspects of the morbid condition, suggesting a multidimensional treatment between rehabilitation exercises for lost skills and psychotherapy. 30 Jun, 2020 https://www.healthdisgroup.us/articles/AGGR-5-122.php While the corona virus does not seem to invade the brain, patients with neurodegenerative diseases do not suffer from specific deficits in their immune system which could put them at increased risk of SARS-CoV-2 infection. So far, experience from the affected regions does not show an apparent increased risk, although there are no systematic data yet available [1]. 25 Jun, 2020 https://www.healthdisgroup.us/articles/AGGR-5-121.php This clinical report presents the case of chronic low back pain in elderly female referring to multilevel (L2-L5) degenerative lumbar spinal stenosis without typical neurogenic claudication and leg pain. Subsequent minimally invasive surgical decompression produced complete resolve of the pain and drastic improvement life quality. This surgery confirmed the pain origin and proves the possibility of sole low back pain as an equivalent of neurogenic claudication. Considering this type of clinical pattern of spinal stenosis can direct general practitioner or other medical professional to correct diagnosis and prompt surgical treatment. 08 Jun, 2020 https://www.healthdisgroup.us/articles/AGGR-5-120.php Hutchinson-Gilford progeria syndrome (HGPS) is the best characterized genetic disorder with premature aging features. Classic HGPS is very rare, sporadic orphan disease, inherited in an autosomal dominant manner without gender or ethnic differences. Children with HGPS appear normal at birth, but begin to develop segmental progeroid symptoms within the first years of life. Patients suffer from sarcopenia, lipodystrophy, diabetes, cataracts, atherosclerosis but not cancer and neurodegenerative diseases. Genetic factors that are associated with this syndrome have been identified, mouse models of disease have been developed, and clinical studies have been conducted for many years. Although many medical and treatment approaches were implemented and showed some efficacy, these therapies could not be considered as a complete cure, and more effective therapeutic approaches were needed for HGPS patients. This report introduces a novel drug called progerinin, which is a binding inhibitor of lamin A and progerin, for patients affected with HGPS. 08 Jun, 2020 https://www.healthdisgroup.us/articles/AGGR-5-119.php Background: The oral health of elderly patients can be treated at home or in the hospital environment with adaptations. This type of home dental care is possible through the synergistic interactions among several health professionals involved in improving the quality of life of dependent and fragile elderly patients. Scientific articles and bibliographic databases on the dental practice-based study in the elderly were searched and analyzed. Search strategy terms were: home care, geriatric dentistry, dental home care, frail elderly, systemic diseases, Alzheimer’s disease and oral health. Inclusion criteria were: published articles in English; articles indexed in databases Pubmed; articles published from 2001 to 2019, totaling 22 references. 05 Jun, 2020 https://www.healthdisgroup.us/articles/AGGR-5-118.php Objective: To evaluate the characteristics and prognosis of hospitalized geriatric COVID-19-positive patients during the first 30 days of the Swiss confinement period. Design: A retrospective case series analyzing the characteristics and disease evolution for 81 patients admitted to the geriatric COVID-19-positive ward during a 30-day period from March 24 to April 22, 2020. Setting and participants: Any COVID-19-positive patients who was admitted to one of four geriatric hospital sites who were >65 years old and did not desire intubation. Methods: Data collection on patients admitted throughout the study period, as well as chart review for those discharged within the 30-day period to ensure that information was complete. 28 May, 2020 https://www.healthdisgroup.us/articles/AGGR-5-117.php Isolated cecum necrosis is a very rare condition. The most common symptom is pain in the right lower quadrant. We are presenting a patient who visited the emergency clinic with right lower quadrant pain and subsequently was diagnosed with cecum necrosis during the operation and underwent a right hemicolectomy. 29 Apr, 2020 https://www.healthdisgroup.us/articles/AGGR-5-115.php An 85-year-old British man admitted to our department in July 2018 with enlarged lumps in cervical, axillary and inguinal sites. He was diagnosed with Follicular lymphoma (Stage 3 Grade 3A). 06 Apr, 2020 https://www.healthdisgroup.us/articles/AGGR-5-114.php Purpose: To compare US and Russian primary care physicians’ attitudes, comfort and experiences providing palliative care. Design: Cross sectional survey. Settings: Iowa, USA and Leningrad Oblast, Russia Participants: Family medicine physicians at University of Iowa and Northwestern State Medical University, St Petersburg, Russia, community practicing family physicians. 07 Feb, 2020 https://www.healthdisgroup.us/articles/AGGR-5-113.php Dignity Therapy (DT) is a psychotherapeutic approach designed to increase patient’s sense of meaning and purpose, offering the opportunity to talk about issues that matter most to them, to share moments they feel were most important and to speak of things they would like to be remembered [1]. DT has been developed and trialled for those near death and had shown efficacy on several psychosocial outcomes [1,2]. However, some recent case reports have been published about the use of DT in non-terminal ill patients with mental disorders such as major depressive disorder and alcohol use disorder [3-5]. 21 Nov, 2019 https://www.healthdisgroup.us/articles/AGGR-4-112.php Psychodynamic psychotherapy provides some key principles and cautionary notes which are relevant to the care of the medically-ill elderly patient. 08 Nov, 2019 https://www.healthdisgroup.us/articles/AGGR-4-111.php The global population aged 60 years and over will reach nearly 2.1 billion by 2050. During the aging process, the strength of the musculoskeletal system decreases and it is essential to be moderately physically action to prevent negative changes in muscle cells. 06 Nov, 2019 https://www.healthdisgroup.us/articles/AGGR-4-110.php Purpose: Despite recent new recommendations from professional societies regarding the management of diabetes in older adults, it is clear that in routine practice, treatment targets are often ill-suited to the health state of polymorbid elderly diabetic patients. 07 Aug, 2019 https://www.healthdisgroup.us/articles/AGGR-4-109.php Background: Anterior knee pain(AKP) was a common complication after total knee replacement(TKR). This condition can be occurred in both patellar resurfacing and non-resurfacing technique. An increase in patellar thickness 1 mm or more postoperatively was associated with lower gain in WOMAC score. 01 Jul, 2019 https://www.healthdisgroup.us/articles/AGGR-4-108.php personal toolbox. I sat with Dr. F and I cried for the whole hour.I had the feeling that he also wanted to cry, but instead, he listened and contained himself. The psychotherapy continued for 4 years, until I felt that I had “cleaned” the memories of the bad times of my life: 15 May, 2019 https://www.healthdisgroup.us/articles/AGGR-4-107.php The objective of this study was to describe the conceptual model and construction of the Vitor Quality of Life Scale for the Elderly (VITOR QLSE). The following approaches were employed to devise and incorporate new items and dimensions into the scale: qualitative study, literature review, focus group and pre-test performed in 30 older adults. The VITOR QLSE was constructed based on the structure of the Quality of Life Index (QLI) and on a specific methodological structure providing dimensions reflecting the quality of life of older adults. The present instrument may serve as a valuable resource in healthcare practice and research that meets the needs of the scientific community, especially in light of the current dearth of instruments in this area. 11 Oct, 2018 https://www.healthdisgroup.us/articles/AGGR-3-106.php Angioedema is a rare but life-threatening side effect of angiotensin-converting enzyme inhibitor (ACEI). It can lead to airway compromise which can be fatal if not treated emergently. CASE: A 69-year-old woman presented to the ED with swollen lips, tongue and change of voice. Her home medications included aspirin, amlodipine, lisinopril and atorvastatin. She was treated with intravenous corticosteroids, diphenhydramine and famotidine. Fiberoptic laryngoscopy showed swollen base of the tongue and arytenoid process necessitating intubation for airway protection. Two units of fresh frozen plasma was given for persistent swelling. Her condition improved, she was extubated and discharged home on the third day. Possible causes of angioedema in her case were food- related, hereditary AE (HAE), and drug -induced. Aspirin and amlodipine related angioedema present early after initiation of these medications. In addition, these drugs typically lead to mast-cell mediated angioedema which is typically associated with a pruritic urticaria. By exclusion, this episode of angioedema was attributed to lisinopril. She was discharged home on aspirin and amlodipine and had no problems on follow up visit. 31 Aug, 2017 https://www.healthdisgroup.us/articles/AGGR-2-105.php Sarcopenia is a progressive loss of skeletal muscle mass and strength with consequent physical disability and negative impact on quality of life. Chemotherapy or surgery efficacy on cancer is influenced by the presence of sarcopenia. 24 Jan, 2017 https://www.healthdisgroup.us/articles/AGGR-2-104.php C9ORF72 gene mutation on chromosome 9 corresponding to a repetition of hexanucleotides (GGGGCC) xn is the most common mutation found in frontotemporal lobar dementia (FTLD) and amyotrophic lateral sclerosis (SLA) [1]. 30 Dec, 2016 https://www.healthdisgroup.us/articles/AGGR-1-103.php Background: The increase in life expectancy has particular relevance to conditions such as cognitive decline and dementia. Dementia is a chronic neurodegenerative disease that is on the rise globally. As the mechanism of dementia has not yet been understood completely; therefore, it is difficult to find a proper and exact cure. 30 Dec, 2016 https://www.healthdisgroup.us/articles/AGGR-1-102.php Rheumatoid arthritis is an autoimmune disorder which can cause temporomandibular joint involvement with clinical symptoms such as pain, swelling, crepitation and movement impairment. Surface erosion is one of the radiologic feature of rheumatoid arthritis and if it is involving carter of the condylar surface, it can be misdiagnosed for the bifid condyle. 12 Dec, 2016 https://www.healthdisgroup.us/articles/AGGR-1-101.php The International League of Dermatological Societies (ILDS) has identified the consequences of skin ageing as one of the most important challenges in global skin health. As we get older, the skin undergoes indeed significant changes – many of which may be attributed to systemic, metabolic, hormonal and neuronal changes.