https://www.clinsurggroup.us/journals/global-journal-of-perioperative-medicine A Peertechz Open Access Journal en-us 06 Nov, 2024 https://www.clinsurggroup.us/articles/GJPM-8-113.php Introduction: Helicobacter pylori (H. pylori) is a bacterium responsible for inflammation of the gastric mucosa. This bacterium causes chronic gastritis in more than 50% of the world’s population and, in about 10 to 15% of cases, can lead to gastric adenocarcinoma, gastroduodenal ulcers, and MALT lymphoma. Notably, H. pylori infection is more prevalent in less developed countries due to poor hygiene, lack of information, and overcrowding. Objective: This study aimed to evaluate the level of knowledge about Helicobacter pylori infection in patients of the Gastroenterology Service from a hospital in Atein 2023. Materials and Methods: An observational, descriptive, cross-sectional, prospective study was conducted at the hospital in Atein Lima, involving 352 adult patients who attended the gastroenterology outpatient clinic between October and December 2023. A validated survey consisting of 20 questions covering sociodemographic data and knowledge about H. pylori infection was used. Statistical analysis was performed using SPSS v.25, using descriptive measures, including frequencies and percentages. Results: The study consisted of 352 patients aged 35 to 60 years, predominantly women. It was identified that 42.6% had a low level of knowledge about H. pylori. Most had low knowledge about conceptual definitions (63.4%) and modes of infection (52.0%). Regarding complications, 44.88% were aware of the relationship with gastric cancer. Conclusion: This study highlights the need to implement educational and awareness strategies to improve knowledge about H. pylori infection among patients. More research is warranted to understand the barriers to greater knowledge and develop effective interventions to overcome them. 27 Sep, 2023 https://www.clinsurggroup.us/articles/GJPM-7-112.php Background: Primary pulmonary myxoid sarcoma is a very rare tumor, with less than 25 cases being described in the literature. When found in the bronchial tree, an R0 resection with post-operative follow-up is sufficient for curative treatment. We present a case of primary pulmonary myxoid sarcoma in a middle-aged man with an associated review of the literature to highlight this rare tumor. Case presentation: A 62-year-old man with a 40-pack-year smoking history presented to the thoracic surgery clinic for evaluation of a suspicious lung nodule. Pre-operative testing revealed a spiculated mass in the left upper lobe and the biopsy was non-diagnostic. The patient was taken for left upper lobectomy tri-segmentectomy with mediastinal lymph node dissection. Final pathology of the nodule revealed primary pulmonary myxoid sarcoma with an Ewing sarcoma breakpoint region 1 on chromosome 22 with activating transcription factor 1 (EWSR-ATF1) fusion transcript consistent with the diagnosis. Conclusion: Primary pulmonary myxoid sarcoma is an exceedingly rare sarcoma of the lung with less than 25 reported cases in the literature. This case report highlights our experience treating primary pulmonary myxoid sarcoma in a middle-aged man, and a review of current treatment recommendations in the available published literature. 28 Sep, 2022 https://www.clinsurggroup.us/articles/GJPM-6-111.php Metastasis is one of the most challenging problems in cancer diagnosis and treatment, as causal factors have yet to be fully disentangled. Prediction of the metastatic status of breast cancer is important for informing treatment protocols and reducing mortality. However, the systems biology behind metastasis is complex and driven by a variety of interacting factors. Furthermore, the prediction of cancer metastasis is a challenging task due to the variation in parameters and conditions specific to individual patients and mutation subtypes. In this paper, we apply tree-based machine learning algorithms for gene expression data analysis in the estimation of metastatic potentials within a group of 490 breast cancer patients. Tree-based machine learning algorithms including decision trees, gradient boosting, and extremely randomized trees are used to assess the variable importance of different genes in breast cancer metastasis. ighly accurate values were obtained from all three algorithms, with the gradient boosting method having the highest accuracy at 0.8901. The most significant ten genetic variables and fifteen gene functions in metastatic progression were identified. Respective importance scores and biological functions were also cataloged. Key genes in metastatic breast cancer progression include but are not limited to CD8, PB1, and THP-1. 24 Feb, 2022 https://www.clinsurggroup.us/articles/GJPM-6-110.php Childhood hydrocephalus is a common disorder in which too much Cerebrospinal Fluid (CSF) accumulates within the ventricles (fluid-containing spaces) of the brain and is usually the-ted by cerebrospinal fluid shunting using a ventriculoperitoneal or ventriculoarterial shunts. The most common condition is hydrocephalus, where there is dilation of the ventricular system due to an obstruction in the flow of CSF or decreased absorption of CSF by the arachnoid villi. Shunting of CSF is the treatment of choice in childhood hydrocephalus. 17 Feb, 2021 https://www.clinsurggroup.us/articles/GJPM-5-109.php Background: Pediatric perioperative mortality is a measure of the quality and safety of surgical care in children. The aim of study was to evaluate the incidence, etiology and pattern of pediatric perioperative mortality (within 24 hours and within 30 days post-surgery) in a teaching hospital in Enugu, Nigeria. Methods: This was a retrospective (STROBE) study of children that died within 30 days following surgery at the pediatric surgery unit of Enugu State University Teaching Hospital, Enugu, Nigeria. Results: There were 2111 pediatric surgical procedures performed during the 5-year study period. Nineteen patients died within 24 hours of surgery which gave a mortality rate of 0.9%. Within 30th post-operative day, further 25 patients expired making it 44 mortalities in total, which correspond to 2.1% mortality rate. The median age of the patients was 2 years. Necrotizing enterocolitis, intussusception and typhoid intestinal perforation were the most common cause of mortality in neonates, infants and children greater than 1 year of age respectively. Overwhelming sepsis was the cause of mortality in most of the patients. Conclusion: Generally, laparotomy for typhoid intestinal perforation was the most common surgical procedure that culminated in the patient’s mortality. Specifically, necrotizing enterocolitis had the highest percentage of deaths. 29 Dec, 2020 https://www.clinsurggroup.us/articles/GJPM-4-108.php Although mechanical valve obstruction is rare. It is a rather fatal complication. Pannus and thrombus are common in etiopathogenesis. Multibl imaging methods such as transthoracic echocardiography, transesophageal echocardiography, synefluoroscopy and computed tomography are used for diagnosis. Surgical treatment is performed in the pannus. In thrombosis, fibrinolytic or surgical treatment can be performed. In this article, we presented the current approach to mechanical valve obstruction. 09 Jul, 2020 https://www.clinsurggroup.us/articles/GJPM-4-107.php Introduction: The objective of the survey study is to the accessible world literature sources and comparative studies dealing with the effectivity of the ERAS concept in the patients after the surgical interventions in the surgical emergency units and to present adoption of concept in the Czech Republic. Method: For searching of the needed information and data they were used the literature sources and comparative studies from the open access and licensed database sources (Scopus, SpringerLink, Medline Complete, ScienceDirect, Web of Science, ProQuest, EBSCOhost, Wiley Online Library). The conclusions of the concrete comparative studies dealing with the conceptual effectivity of the perioperative care ERAS were analysed. On the analytical base of the gained information drawing from the accessible literature and from 8 quantitative studies published in the years 2009-2013. Results: It is clear that following of the ERAS protocol principle in the surgical workplaces in the Czech Republic is adopted only in the limitation of the routine application of the nasogastric probe, application of epidural analgesia and parenteral preoperative nutritional support if enteral not possible. Conclusion: The positive effect of the new way of the perioperative care, ERAS is proved as for the qualitative improvement of the treatment and nursing process, as for decreasing of the postoperative complications and shortening of the hospitalization period including decreasing of the economic expenditures connected to the treatment and hospitalization of the surgical patients. In comparison with established ERAS protocol, in the Czech Republic the principles are put into effect less significantly. The mentioned experiences and results can be the useful source for the next surgical workplaces. 12 Jul, 2019 https://www.peertechzpublications.org/articles/GJPM-3-106.pdf Objective: To investigate the pre-operative, intra-operative and post-operative risk factors associated with aspiration pneumonia in patients undergoing abdominal surgery. We also aimed to identify the risk-factors that were associated with increased mortality. Design: Retrospective audit. 12 Jul, 2019 https://www.clinsurggroup.us/articles/GJPM-3-106.php Objective: To investigate the pre-operative, intra-operative and post-operative risk factors associated with aspiration pneumonia in patients undergoing abdominal surgery. We also aimed to identify the risk-factors that were associated with increased mortality. Design: Retrospective audit. Setting: Single regional centre located in Australia. Participants: Patients that were admitted under the general surgery team at a regional hospital in Australia were reviewed to confirm the presence of aspiration pneumonia as a complication during their admission. A total of 19 patients were identified that had a confirmed diagnosis of aspiration pneumonia between December 2013 and November 2016. The medical record of each case of aspiration pneumonia was reviewed in order to identify high-risk features for the development of aspiration pneumonia. 16 Nov, 2017 https://www.clinsurggroup.us/articles/GJPM-1-105.php Traditional preoperative assessment tools use patients’ comorbidities to predict surgical outcomes, however, some functional, social and behavioral factors are known to predict surgical outcomes. Capturing functional, social and behavioral factors by incorporating patient reported measures (PROMs) into preoperative practice may be responsive to perioperative management and contribute to improved outcomes. 20 Mar, 2017 https://www.clinsurggroup.us/articles/GJPM-1-104.php Background: First Case on Time Starts (FOTS) are an important Operating Room performance metric. The study aim is to show how implementation of process improvement (PI) solutions and an electronic health record (EHR) led to a progressive, signifi cant, and sustainable improvement in FOTS. 16 Feb, 2017 https://www.clinsurggroup.us/articles/GJPM-1-103.php Introduction: Prediction of readmission as a result of either delayed presentation of infection, or worse an anastomotic leak is diffi cult. 19 Jan, 2017 https://www.clinsurggroup.us/articles/GJPM-1-102.php In some situations, tissue hypoxia may exist despite normal values obtained by conventional haemodynamic monitoring such as arterial blood pressure, central venous pressure, heart rate, and urine output. The study was performed in early postoperative period after major abdominal surgery in 160 patients and was conducted in the following stages: 1- admission from operating room; 2 - in 1-3 hours; 3 - 4-7 hours; 4 - 8-12 hours; 5 - after 13-24 hours after the surgery. 17 Jan, 2017 https://www.clinsurggroup.us/articles/GJPM-1-101.php Short Communication Major surgery is a considerable physiologic insult that can be associated with significant morbidity and mortality. The prevention of perioperative morbidity is a determining factor in providing high-quality in health care, since the occurrence of postoperative complications adversely affects postoperative survival and increase healthcare costs