Research Interest: To explore the molecular biology and their use in genetic toxicology. currently held to identify the genetic research hazard of chemicals, physical and biological

Research Interest: Biological activity of blood platelets; inflammatory properties of platelets; interaction of blood platelets with the cells of the immune system; autoimmune diseases; activation and platelet reactivity in neurodegenerative diseases (multiple sclerosis); proteome, transcriptome and metabolome of platelets; molecular markers of platelets in the diagnosis of acute coronary syndromes

Research Interest: Methodology of solid phase peptide synthesis and synthetic peptides with bioactivity

Research Interest:  A versatile biotechnologist with research experience ranging from searching for novel microbial enzymes using classical and metagenomic approaches, genetic engineering to tailor them for specific applications, fermentation, downstream processing and their biotechnological application. Biotechnological applications range from developing “Green Chemistry technologies”/processes, developing antimicrobial systems, and systems/and or products for preventing, monitoring and therapy of oxidative stress related human diseases (cancer, cardiovascular, respiratory, atherosclerosis, diabetes, neurodegenerative diseases).

Research Interest: Gentics; Tree Genetic Improvement; Plant Biotechlology

Research Interest:  Drug Delivery, Pharmacokinetics, Controlled Release, Drug Targeting, Prodrug

Research Interest: Regulation of extracellular matrix genes and growth factors by potential anti-skin aging, anti-carcinogenic or wound repair agents in normal or cancer cells:Area of Expertise: Biochemistry and Cell/Molecular Biology; Biotechnology: Cell culture, Gene Regulation (protein, mRNA, promoter levels), Extracellular matrix (collagen, matrixmetalloproteinases, elastin, fibrillin), Growth factors/cytokines (tranaforming growth factor-b, interleukins), Oxidative Stress/Reactive Oxygen species, Antioxidants, Apoptosis, Toxicity, Angiogenesis/Metastasis.

Research Interest: Aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetes and diabetic osteoporosis, cancer biology, and cancer bone metastasis. Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi generated regucalcin transgenic rats, which were registered as international patents (USA, EU, Japan, and Korea), and this animal was found to induce osteoporosis and hyperlipidemia. Moreover, Dr. Yamaguchi proposed the potential role of regucalcin as a key suppressor protein in carcinogenesis.  Currently, the research of regucalcin is focused as a scientific topic 

Research Interest: Studying the pathogenic process in betanodavirus and iridovirus infection in grouper GF-1 and larval grouper fish systems. His laboratory pioneered the use of grouper model to study betanodavirus in vivo on brain damaged, which as a model. 

Research Interest: Food Processing, health food and cosmetics, Research of Chinese herbal medicine research, Agricultural biotechnology, Supercritical fluid, and Mycology 

Research Interest:  Phosphate-based glass production and characterisation including Phosphate glass-fibre (PGF) production. He is also currently working on resorbable polymer composites, mainly for bone repair applications. His other interests include, calcium phosphate cements, microsphere technologies, drug delivery systems, Tissue Engineering and Regenerative Medicine applications

Research Interest: Biomedical applications of Nanotechnology, Nano Particulate Drug Delivery systems, Antibody mediated drug delivery systems, Nano-Nutraceuticals and Nano dispersed Systems, and educational research

Research Interest:  Obesity, metabolic syndrome, diabetes type 2,dyslipidemia,hypertension.

Research Interest: Polymeric Biomaterials and Green Materials: -Synthesis and Characterization, Surface Modification, and Patterning (soft and dip-pen lithography) and Polymers processing, Synthesis of Polyurethanes/Polyesters and Bio-based resins. Nanomaterials and Energy Materials: Polymer-HA or Polymer-CNT Nanocomposites, Synthesis of Nanofibers and Nanoparticles for cancer drug delivery, Chemical modification of Nanodiamond particles and Metallization of CNTs, Polymeric and silica Nanorods as reinforcing fillers for dental restoration materials for flowable composites), Polymer/graphene composite materials and Polymer/polyoxometalate composites for energy applications. Tissue Engineering/ Drug Delivery: Polymeric 3D-Nanofibrous Scaffolds for Bone, Vascular, Neural and Dental, Salivary glands and multifunctional nanoparticles for lung cancer drug and growth factor delivery, Nasal/mucosal delivery of therapeutics), Electrospining and Force-spinning techniques for polymer and ceramic composite nanofabrication. Additive bio-manufacturing and We-laid Process for biomaterials/scaffolds of complex tissues and interfaces. Characterization of Materials: Microscopic and Spectroscopic characterization (SEM, AFM, FT-IR, XPS), mechanical properties characterization (Tensile, compression, dynamic mechanical (DMA) and nanoindentation), thermal properties (TGA, DSC, TMA) and Rheological characterization of polymeric biomaterials, nanomaterials and hybrid polymer/inorganic composites and in vitro Cell Studies for biocompatibility and toxicity. In Vitro Evaluation of nano-structured materials/ nanodiamond wear-debris from orthopedic joint implants: Nanoscaled wear-debris isolation from Hip and knee Simulator (AMTI) and its inflammatory effect evaluation.

Research Interest: Pharmacology/Toxicology Isolation and Identification of Natural products, Drug Discovery and Development, Cellular and Molecular Biology of Diseases