Research Interest: To explore the molecular biology
and their use in genetic toxicology. currently held to identify the genetic
research hazard of chemicals, physical and biological
Research Interest: Biological activity of blood
platelets; inflammatory properties of platelets; interaction of blood platelets
with the cells of the immune system; autoimmune diseases; activation and
platelet reactivity in neurodegenerative diseases (multiple sclerosis);
proteome, transcriptome and metabolome of platelets; molecular markers of
platelets in the diagnosis of acute coronary syndromes
Research Interest: Methodology of solid phase
peptide synthesis and synthetic peptides with bioactivity
Research Interest: A versatile biotechnologist with research experience
ranging from searching for novel microbial enzymes using classical and
metagenomic approaches, genetic engineering to tailor them for specific
applications, fermentation, downstream processing and their biotechnological
application. Biotechnological applications range from developing “Green
Chemistry technologies”/processes, developing antimicrobial systems, and
systems/and or products for preventing, monitoring and therapy of oxidative
stress related human diseases (cancer, cardiovascular, respiratory,
atherosclerosis, diabetes, neurodegenerative diseases).
Research Interest: Gentics; Tree Genetic
Improvement; Plant Biotechlology
Research Interest: Drug Delivery, Pharmacokinetics, Controlled
Release, Drug Targeting, Prodrug
Research Interest: Regulation of extracellular matrix genes and growth factors by potential anti-skin aging, anti-carcinogenic or wound repair agents in normal or cancer cells:Area of Expertise: Biochemistry and Cell/Molecular Biology; Biotechnology: Cell culture, Gene Regulation (protein, mRNA, promoter levels), Extracellular matrix (collagen, matrixmetalloproteinases, elastin, fibrillin), Growth factors/cytokines (tranaforming growth factor-b, interleukins), Oxidative Stress/Reactive Oxygen species, Antioxidants, Apoptosis, Toxicity, Angiogenesis/Metastasis.
Research Interest: Aspect of biochemistry,
molecular biology, endocrinology, metabolism, nutrition, pharmacology, and
toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone
biology, nutritional factor and osteoporosis prevention, diabetes and diabetic
osteoporosis, cancer biology, and cancer bone metastasis. Dr. Yamaguchi
discovered two novel proteins and genes; cell signaling suppressor protein
(named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene
promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi
generated regucalcin transgenic rats, which were registered as international
patents (USA, EU, Japan, and Korea), and this animal was found to induce
osteoporosis and hyperlipidemia. Moreover, Dr. Yamaguchi proposed the potential
role of regucalcin as a key suppressor protein in carcinogenesis. Currently, the research of regucalcin is
focused as a scientific topic
Research Interest: Studying the pathogenic process
in betanodavirus and iridovirus infection in grouper GF-1 and larval grouper
fish systems. His laboratory pioneered the use of grouper model to study
betanodavirus in vivo on brain damaged, which as a model.
Research Interest: Food Processing, health food and
cosmetics, Research of Chinese herbal medicine research, Agricultural
biotechnology, Supercritical fluid, and Mycology
Research Interest: Phosphate-based glass production and characterisation including Phosphate glass-fibre (PGF) production. He is also currently working on resorbable polymer composites, mainly for bone repair applications. His other interests include, calcium phosphate cements, microsphere technologies, drug delivery systems, Tissue Engineering and Regenerative Medicine applications
Biomedical applications of Nanotechnology, Nano Particulate Drug Delivery
systems, Antibody mediated drug delivery systems, Nano-Nutraceuticals and Nano
dispersed Systems, and educational research
Research Interest: Obesity, metabolic syndrome, diabetes type 2,dyslipidemia,hypertension.
Research Interest: Polymeric Biomaterials and Green Materials: -Synthesis and Characterization, Surface Modification, and Patterning (soft and dip-pen lithography) and Polymers processing, Synthesis of Polyurethanes/Polyesters and Bio-based resins. Nanomaterials and Energy Materials: Polymer-HA or Polymer-CNT Nanocomposites, Synthesis of Nanofibers and Nanoparticles for cancer drug delivery, Chemical modification of Nanodiamond particles and Metallization of CNTs, Polymeric and silica Nanorods as reinforcing fillers for dental restoration materials for flowable composites), Polymer/graphene composite materials and Polymer/polyoxometalate composites for energy applications. Tissue Engineering/ Drug Delivery: Polymeric 3D-Nanofibrous Scaffolds for Bone, Vascular, Neural and Dental, Salivary glands and multifunctional nanoparticles for lung cancer drug and growth factor delivery, Nasal/mucosal delivery of therapeutics), Electrospining and Force-spinning techniques for polymer and ceramic composite nanofabrication. Additive bio-manufacturing and We-laid Process for biomaterials/scaffolds of complex tissues and interfaces. Characterization of Materials: Microscopic and Spectroscopic characterization (SEM, AFM, FT-IR, XPS), mechanical properties characterization (Tensile, compression, dynamic mechanical (DMA) and nanoindentation), thermal properties (TGA, DSC, TMA) and Rheological characterization of polymeric biomaterials, nanomaterials and hybrid polymer/inorganic composites and in vitro Cell Studies for biocompatibility and toxicity. In Vitro Evaluation of nano-structured materials/ nanodiamond wear-debris from orthopedic joint implants: Nanoscaled wear-debris isolation from Hip and knee Simulator (AMTI) and its inflammatory effect evaluation.
Research Interest: Pharmacology/Toxicology Isolation
and Identification of Natural products, Drug Discovery and Development, Cellular
and Molecular Biology of Diseases
Published On: June 10, 2023 | Pages: 009 - 016Abstract View Full Article View
Published On: March 16, 2023 | Pages: 001 - 008Abstract View Full Article View
Published On: June 14, 2022 | Pages: 009 - 022Abstract View Full Article View
Published On: May 25, 2022 | Pages: 001 - 008Abstract View Full Article View
Published On: January 12, 2021 | Pages: 001 - 005Abstract View Full Article View
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Published On: May 28, 2020 | Pages: 007 - 012Abstract View Full Article View
Published On: May 16, 2020 | Pages: 001 - 006Abstract View Full Article View
Published On: August 10, 2018 | Pages: 001 - 007Abstract View Full Article View
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