Research Interest: Microbiology, Molecular Biology, Molecular genetics, Agricultural Biotechnology, Recombinant DNA Technology, Medical Biotechnology, Industrial Biotechnology, Nano Biotechnology, Immunology, Bacterial viruses, Virus-host Interactions, Molecular Virology, DNA Virus, Phage therapy, Antiviral, Bioinformatics, Sythetic biology, Omics

Research Interest: Cancer and Autoimmune Disease Therapy and Mechanisms; Molecular and Cellular Immunology; Molecular Biology; Antibody Engineering; Recombinant Proteins; Protein-Protein Interaction; Gene Therapy; Animal and Cell Models; Signal Transduction, Apoptosis, and Molecular Mechanisms; Protein Expression, Purification and Function; Genome/Proteome Sciences

Research Interest: Marine Bacteria Isolation, Identification; Bacterial Natural Products (Isolation, Identification, Function); Bacterial Enzymes Isolation And Function Assays; Bacteria Genomics, Genetics And Metabolism.

Professional Experience:

Associate researcher (2013-present), Gene Engineering Laboratory, Feed Research Institute, CAAS;                                             

Assistant researcher (2009-2013), Gene Engineering Laboratory, Feed Research Institute, CAAS;

Post doctor (2006-2009), College of Forestry, Beijing Forestry University.

Research Interest: Bacteriology, Cellular or Molecular Biology, Biochemistry and Biotechnology, Antimicrobial Peptides or Antibiotics.

Publications:

1)    Li ZZ, Mao RY, Teng D, Hao Y, Chen HX, Wang XM*, Wang JH. Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus. Sci Rep, 2017, 7: 12124. (corresponding author) (IF 4.259)
2)    Yang N, Liu XH, Teng D, Li ZZ, Wang XM*, Mao RY , Wang X, Hao Y, Wang JH. Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis. Sci Rep, 2017, 7: 3392. (corresponding author) (IF 4.259)
3)    Hao Y, Yang N, Wang XM*, Teng D, Mao RY, Wang X, Li Z, Wang JH. Killing of Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide by 17-residue bovine lactoferricins: improved activity of Trp/Ala-containing molecules. Sci Rep, 2017, 7:44278. (corresponding author)
4)    Li ZZ, Wang XM*, Wang X, Teng D, Mao RY, Hao Y, Wang JH. Research advances on plectasin and its derivatives as new potential antimicrobial candidates. Process Biochem, 2017, 56:62-70. (corresponding author) (IF 2.5)
5)    Wang X, Wang XM, Hao Y, Teng D, Wang JH. Research and development on lactoferrin and its derivatives in China from 2011–2015. Biochem Cell Biol, 2017, 95: 162-170. (co-first authorship) (IF 1.895)
6)    Wang X, Teng D, Guan QF, Mao RY, Hao Y, Wang XM*, Yao JH, Wang JH. Escherichia coli outer membrane protein F (OmpF): an immunogenic protein induces cross-reactive antibodies against Escherichia coli and Shigella. AMB Expr, 2017, 7: 155 (corresponding author) (IF 1.825)
7)    Yang N, Wang XM*, Teng D, Mao RY, Hao Y, Feng XJ, Wang JH. Deleting the first disulphide bond in an arenicin derivative enhances its expression in Pichia pastoris. Lett Appl Microbiol. 2017, 65(3), 241-248. (corresponding author) (IF 1.575)
8)    Wang XM, Teng D, Mao RY, Yang N, Hao Y, Wang JH. Combined systems approaches reveal a multistage mode of action of a marine antimicrobial peptide against pathogenic Escherichia coli and its protective effect against bacterial peritonitis and endotoxemia. Antimicrob Agents Chemother. 2016, 61(1). pii: e01056-16. (IF 4.302)
9)    Yang N, Wang XM*, Teng D, Mao RY, Hao Y, Zong LF, Feng XJ, Wang JH. Modification and characterization of a new recombinant marine antimicrobial peptide N2. Process Biochem, 2016, 51(6):734-739. (corresponding author) (IF 2.5)
10)    Guan QF, Wang X, Wang XM*, Teng D, Wang JH. In silico analysis and recombinant expression of BamA protein as a universal vaccine against Escherichia coli in mice. Appl Microbiol Biotechnol. 2016, 100(11):5089-98. (corresponding author) (IF 3.42)
11)    Wang X, Teng D, Guan QF, Mao RY, Hao Y, Wang XM, Yao JH, Wang JH. Paving the way to construct a new vaccine against Escherichia coli from its recombinant outer membrane protein C via model mouse. Process Biochem, 2015, 50: 1194-1201. (co-first authorship) (IF 2.5)
12)    Guan QF, Wang X, Wang XM, Teng D, Mao R Y , Zhang Y, Wang JH. Recombinant outer membrane protein A induces a protective immune response against Escherichia coli infection in mice. Appl Microbiol Biotechnol. 2015, 99(13):5451-60. (co-first authorship) (IF 3.42)
13)    Xi D, Wang XM, Teng D, Mao RY, Zhang Y, Wang XJ, Wang JH. Mechanism of action of the tri-hybrid antimicrobial peptide LHP7 from lactoferricin, HP and plectasin on Staphylococcus aureus. Biometals, 2014, 27 (5): 957-968. (co-first authorship) (IF 2.183)
14)    Wang XJ, Wang XM, Teng D, Zhang Y, Mao R Y , Xi D, Wang JH. Candidacidal mechanism of the arenicin-3-derived peptide NZ17074 from Arenicola marina. Appl Microbiol Biotechnol. 2014, 98(17):7387-98. (co-first authorship) (IF 3.42)
15)    Wang XJ, Wang XM, Teng D, Zhang Y, Mao RY, Wang JH. Recombinant production of the antimicrobial peptide NZ17074 in Pichia pastoris using SUMO3 as a fusion partner. Lett Appl Microbiol. 2014, 59(1):71-8. (co-first authorship) (IF 1.575)
16)    Wang XM, Teng D, Guan QF, Tian F, Wang JH. Detection of genetically modified crops using multiplex asymmetric polymerase chain reaction and asymmetric hyperbranched rolling circle amplification coupled with reverse dot blot. Food Chem, 2015, 173: 1022-1029. (IF 4.529)
17)    Wang XM, Teng D, Guan QF, Tian F, Wang JH. Detection of Roundup Ready soybean by loop-mediated isothermal amplification combined with a lateral-flow dipstick. Food Control, 2013, 29: 213-220. (IF 3.496)
18)    Wang XM, Teng D, Yang YL, Tian F, Guan QF, Wang JH. Construction of a reference plasmid containing ten targets for the detection of genetically modified crops. Plasmid, 2013, 69(1): 108-113. (IF 1.545)
19)    Wang XM, Teng D, Guan QF, Tian F, Wang JH. Comparison of three DNA extraction methods for feed products and four amplification methods for the 5´-junction fragment of Roundup Ready soybean. J Agri Food Chem, 2012, 60(18): 4586-4595. (IF 3.154)
20)    Wang XM, Teng D, Yang YL, Tian F, Guan QF, Wang JH. Construction of reference molecule containing eight targets for the detection of genetically modified crops. Appl Microbiol Biotechnol, 2011, 90(2): 721-731. (IF 3.42)

Research Interest: Molecular Biology, Histology and Cytology, Electrophysiology Animal study