Chloramphenicol is a widely used topical ointment applied routinely for ocular and periorbital infections due to its wide spectrum of anti-bacterial activity. Local delayed hypersensitivity reaction to chloramphenicol is a well reported but uncommon adverse effect, and has been reported to mismanaged initially as an infective cellulitis. The confirmatory tests for drug allergy are often not possible in developing countries and hence, the diagnosis is usually made with high index of clinical suspicion. Hereby, we are reporting a case of local hypersensitivity reaction to chloramphenicol after ocular use for adenexal infection, which was diagnosed with high index of suspicion without any diagnostic test, and was managed timely and successfully.

Readmore... DOI: 10.17352/2455-1414.000006

Purpose: To compare central corneal thickness (CCT) among glaucoma patients, glaucoma suspects, and normal subjects and to determine its association with glaucoma severity in Nepalese population.
Methods: This study included 400 eyes (149 glaucoma, 157 glaucoma suspects, 94 controls) of 400 participants examined in a glaucoma clinic and eye OPD in Nepal. CCT was measured by ultrasonic pachymetry.

Readmore... DOI: 10.17352/2455-1414.000007

Bleb failure after initially successful glaucoma surgery still constitutes a major challenge in management of glaucoma patients.
Needling is considered a simple surgical technique that can solve a major problem like failure of glaucoma surgery.
The introduction of antimetabolite in ophthalmology greatly enhances the results of needling as well as the initial trabeculectomy.

Readmore... DOI: 10.17352/2455-1414.000008

Purpose: To present a case of familial Mediterranean fever with eye involvement as the initial sign of multiple sclerosis.
Method: A 13-year-old boy with familial mediterranean fever (FMF) presented with sudden loss of vision in his right eye.

Readmore... DOI: 10.17352/2455-1414.000009

The term "posterior polar hemispheric choroidal dystrophy" was first used by Yannuzzi to describe the annular, hemispheric loss of retinal pigment epithelium and choriocapillaris[1].Since then, there have been no further reports on this rare condition.

Readmore... DOI: 10.17352/2455-1414.000010