Tuberculosis is described during the use of monoclonal antibodies against tumour necrosis factor (TNF) for Crohn's disease treatment. We report a case of a 44 year old man that developed fever, night sweats and weight loss during immunosuppressive and anti-TNF therapy for Crohn's disease.
Helicobacter pylori Infection and Hematologic Disorders: what do We Really Know?
One of the most important events on gastroenterology certainly was the isolation of Helicobacter pylori (H. pylori) by Barry Marshall and Robin Warren in 1983 [1], occurrence which redirected our understanding of the pathophysiology of gastrointestinal diseases.
A Review on Therapeutic Management of Chronic Hepatitis B Infection
The current therapeutic goal in the management of chronic hepatitis B (CHB) infection is to persistently suppress hepatitis B virus (HBV) replication and prevent its progression to liver failure and the development of hepatocellular carcinoma (HCC). At present, the therapeutic strategies for CHB includes either a short course of pegylated-interferon-alfa (PEG-IFNα) and/or a long term course of nucleos(t)ide analogues (NA's). NA's are more preferable to PEG-IFNα, majorly for its easier route of administration and excellent tolerance and safety profiles.
Successful Treatment of Stomal Variceal Bleeding with Percutaneous Injection Sclerotherapy
Bleeding from ectopic varices is often massive and fatal with portal hypertension, and stomal varices can occur in patients with stoma. We aimed to treat a hepatitis B surface antigen positive 69 year-old male with liver cirrhosis associated hepatocellular carcinoma with bleeding stomal varices using percutaneous injection sclerotherapy. Percutaneous injection sclerotherapy was performed under fluoroscopy using 5% ethanolamine oleate with iopamidol (EOI) with a 25 gauge disposable injection needle; 5ml of 5% EOI were injected gradually.
Benign lesions of the colon are infrequent and with a low percentage of appearance. Colon lipomas are in the third place of benign tumors after adenomas and smooth muscle [1,5]. Colonic lipomas are benign non epithelial tumors of soft texture and mesenchymal origin; generally they grow from mature adipocytes.
The Effect on Gastric Emptying of Telaprevir-Based Triple Therapy for Chronic Hepatitis C Patients
Aim: We evaluated food intake in telaprevir-based triple therapy (telaprevir, pegylated-interferon, and ribavirin) and its relation to Gastric Emptying (GE).
Methods: 17 patients received telaprevir combined with pegylated interferon plus ribavirin. The GE study was carried out using the 13C-acetate breath test and GE time was expressed as the peak time of 13CO2 excretion (Tmax).
Beta-(1,3/1,6)-D-glucan Helps to Decrease Opportunistic Infections in Crohn's Disease Patients Treated with Biological Therapy
Background: Secondary intercurrent infectious in patients with inflammatory bowel diseases (IBD) represent a very important problem in daily clinical practice because of their significant contribution to quality of life and work ability.
Implementation and Implication of Ignoring Small Polyps at Colonoscopy
Background and Aim: CT colonography has promoted a new paradigm, that up-to 2 polyps =5mm can be left in-situ and followed. In contrast, endoscopists identify and remove all colorectal polyps, regardless of size. We evaluated whether and how endoscopists might implement a plan of ignoring small polyps in clinical practice.