Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2].
Its pharmacokinetics and pharmacodynamics can be influenced by different factors as age, inhaled anesthetics, hepatic and renal insufficiency, hypothermia, gender and obesity [3-8].
Rocuronium has been shown to cause less histamine release and cardiovascular instability than benzylisoquinolinum neuromuscular blocking agents such as atracurium and mivacurium , however it can act as an antigen: in our clinical experience three acute reactions occurred after its administration in the same patient.
Keywords: Rocuronium; Hypotension; Severe obesity
Published on: Sep 6, 2014 Pages: 13-15
Full Text PDF
Full Text HTML
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
University of Parma, Italy
International Journal of Dermatology and Clinical Research
Lund University, Sweden
Annals of Environmental Science and Toxicology
Nikolaos A Chrysanthakopoulos
National and Kapodistrian University of Athens , Greece
Journal of Dental Problems and Solutions
William CS Cho
Queen Elizabeth Hospital, Hong Kong
International Journal of Immunotherapy and Cancer Research
Jose Manuel Ramia-Angel
Guadalajara University Hospital , Spain
Journal of Surgery and Surgical Research
Wei Min HUANG
Nanyang Technological University, Singapore
Archive of Biomedical Science and Engineering
International Iberian Nanotechnology Laboratory (INL), Portugal
International Journal of Nanomaterials, Nanotechnology and Nanomedicine
Ohio State University, USA
Open Journal of Bioinformatics and Biostatistics
Dr. Pierre Guertin
Laval University, Canada
Archive of Gerontology and Geriatrics Research
Marco Matteo Ciccone
University of Bari , Italy
Archives of Organ Transplantation
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."